417724-71-1

Basic information

• Product Name: 4-(4-nitrophenoxy)thieno[2,3-d]pyrimidine
• Synonyms: 4-(4-nitrophenoxy)thieno[2,3-d]pyrimidine
• CAS NO: 417724-71-1
• Molecular Weight: 273.272
• Mol File: 417724-71-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(4-nitrophenoxy)thieno[2,3-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-nitrophenoxy)thieno[2,3-d]pyrimidine(417724-71-1)
• EPA Substance Registry System: 4-(4-nitrophenoxy)thieno[2,3-d]pyrimidine(417724-71-1)

Safety Data

• Hazardous Substances Data: 417724-71-1(Hazardous Substances Data)

Upstream product

• 4651-81-4 Methyl 2-aminothiophene-3-carboxylate 
• 14080-50-3 thieno[2,3-d]pyrimidin-4(3H)one 
• 14080-59-2 4-chlorothieno[2,3-d]pyrimidine 
• 100-02-7 4-nitro-phenol 

Downstream Products

• 1099669-23-4 4-(thieno[2,3-d]pyrimidin-4-yloxy)aniline 
• 417720-88-8 N-(3-Fluorophenyl)-N'-(4-(thieno[2, 3-d]pyrimidin-4-yloxy)phenyl)urea 

Relevant articles and documents

Preparation and application of thiophene pyrimindine compound containing heteroaryl amide structure

The invention relates to a thiophene pyrimindine compound containing a heteroaryl amide structure shown in the general formula I, and a pharmaceutically acceptable salt, an aquo-complex, a solvate and a predrug of the thiophene pyrimindine compound containing the heteroaryl amide structure, wherein the implications of the substituent group R1, X, Y, D and Z are shown in the description. The invention further relates to a strong effect of inhibiting c-Met kinase of the compound shown in the general formula I, and also relates to application of the compound and the pharmaceutically acceptable salt, the aquo-complex, the solvate and the predrug of the thiophene pyrimindine compound to preparing a medicine used for treating diseases caused by abnormal high expression of the c-Met kinase, particularly application to preparing a medicine for treating and/or preventing cancers.