41832-84-2Relevant articles and documents
Studies in Potential Filaricides : Part XII - A Convenient Synthesis of 1-Ethyl-3-(2-substituted ethyl)hexahydropyrimidin-2-ones
Dubey, Sushil Kumar,Sharma, Satyavan,Iyer, R. N.,Anand, Nitya
, p. 170 - 171 (2007/10/02)
1-Ethyl-3-(2-substituted ethyl)hexahydropyrimidin-2-ones (6a-c) have been synthesized by a convenient method and have been tested against Litomosoides carinii infection in cotton rats.None of them shows antifilarial activity at a dose of 30 mg/kg given for 6 days.