418766-37-7

Basic information

• Product Name: Acetic acid, [4-[2-hydroxy-1-(trimethylsilyl)ethyl]phenoxy]-, 2-propenyl ester
• CAS NO: 418766-37-7
• Molecular Formula: C16H24O4Si
• Molecular Weight: 308.45
• Mol File: 418766-37-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Acetic acid, [4-[2-hydroxy-1-(trimethylsilyl)ethyl]phenoxy]-, 2-propenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, [4-[2-hydroxy-1-(trimethylsilyl)ethyl]phenoxy]-, 2-propenyl ester(418766-37-7)
• EPA Substance Registry System: Acetic acid, [4-[2-hydroxy-1-(trimethylsilyl)ethyl]phenoxy]-, 2-propenyl ester(418766-37-7)

Safety Data

• Hazardous Substances Data: 418766-37-7(Hazardous Substances Data)

Upstream product

• 754-05-2 ethenyltrimethylsilane 
• 418766-35-5 2-[4-(1-ethoxyethyloxy)phenyl]-2-trimethylsilyl-ethanol 
• 16722-09-1 trimethylsilyloxirane 
• 2916-14-5 allyl chloroacetate 
• 418766-36-6 2-(4-hydroxyphenyl)-2-trimethylsilyl-ethanol 

Downstream Products

• 663191-87-5 allyl 4-[2-(N-fluorenylmethoxycarbonyl-L-prolyloxy)-1-(trimethylsilyl)-ethyl]-phenoxyacetate 
• 1234478-43-3 C₄₂H₅₄N₂O₉Si 
• 418766-42-4 (4-{2-[(9H-fluoren-9-ylmethoxycarbonylamino)-acetoxy]-1-trimethylsilanyl-ethyl}-phenoxy)-acetic acid 
• 886599-30-0 (R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-trienylsulfanyl)-propionic acid 2-(4-carboxymethoxy-phenyl)-2-trimethylsilanyl-ethyl ester 
• 886599-29-7 (R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-trienylsulfanyl)-propionic acid 2-(4-allyloxycarbonylmethoxy-phenyl)-2-trimethylsilanyl-ethyl ester 
• 461643-20-9 allyl 4-[2-(N-fluorenylmethoxycarbonyl-L-isoleucyloxy)-1-(trimethylsilyl)-ethyl]-phenoxyacetate 
• 461643-21-0 (9H-fluoren-9-ylmethoxycarbonylamino)-acetic acid 2-(4-allyloxycarbonylmethoxy-phenyl)-2-trimethylsilanyl-ethyl ester 

Relevant articles and documents

Solid-phase synthesis of palmitoylated and farnesylated lipopeptides employing the fluoride-labile PTMSEL linker

Acid- and base-labile S-palmitoylated and S-farnesylated lipopeptides can be synthesized in high overall yield employing the (2-phenyl-2-trimethylsilyl) ethyl (PTMSEL) linker for anchoring to and release under almost neutral conditions from the solid support.

The (2-phenyl-2-trimethylsilyl) ethyl-(PTMSEL) linker - A novel linker for the solid-phase synthesis of protected peptides and glycopeptides cleavable with fluoride

Suitable for the immobilization of carboxylic acids, the (2-phenyl-2-trimethylsilyl)ethyl linker was developed as a novel, fluoride-sensitive anchor. Cleavage with tetrabutylammonium fluoride (TBAF) trihydrate in CH2Cl2 under almost