419573-58-3Relevant articles and documents
Design of novel antibiotics that bind to the ribosomal acyltransfer site
Haddad, Jalal,Kotra, Lakshmi P.,Llano-Sotelo, Beatriz,Kim, Choonkeun,Azucena Jr., Eduardo F.,Liu, Meizheng,Vakulenko, Sergei B.,Chow, Christine S.,Mobashery, Shahriar
, p. 3229 - 3237 (2002)
The structure of neamine bound to the A site of the bacterial ribosomal RNA was used in the design of novel aminoglycosides. The design took into account stereo and electronic contributions to interactions between RNA and aminoglycosides, as well as a ran
