41961-03-9Relevant articles and documents
Total Synthesis of the Proposed Microcyclamides MZ602 and MZ568
Liu, Yi,Zhao, Xiangyun,Wang, Hongbo,Liu, Huili,Sui, Zhuyin,Yan, Bingfei,Du, Yuguo
, p. 1065 - 1073 (2020/12/21)
The first convergent total synthesis for the proposed structures of microcyclamides MZ602 (1) and MZ568 (2) has been accomplished in 11 linear steps with 12.5 and 16.8% overall yield, respectively. Key features of the syntheses include a one-pot cascade r
Bromelain catalyzed synthesis of peptides in organic solvent
Tai, Dar-Fu,Fu, Shu-Lin
, p. 179 - 183 (2007/10/03)
For the first time, immobilized bromelain was shown to maintain high catalytic activity in organic solvent and to form peptide bonds. It requires only 7 hours to obtain Cbz-Gly-L-Leu-OMe in 85% yield. The precursor of aspartame (Cbz-L-Asp-L-Phe-OMe) and other dipeptides were also synthesized by this method.