42060-55-9

Basic information

• Product Name: N-benzyl-N-methylbenzenesulfonamide
• Synonyms: N-benzyl-N-methylbenzenesulfonamide
• CAS NO: 42060-55-9
• Molecular Weight: 261.345
• Mol File: 42060-55-9.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: N-benzyl-N-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-N-methylbenzenesulfonamide(42060-55-9)
• EPA Substance Registry System: N-benzyl-N-methylbenzenesulfonamide(42060-55-9)

Safety Data

• Hazardous Substances Data: 42060-55-9(Hazardous Substances Data)

Upstream product

• 837-18-3 N-benzylbenzenesulfonamide 
• 74-88-4 methyl iodide 
• 103-67-3 benzyl-methyl-amine 
• 98-09-9 benzenesulfonyl chloride 
• 80-17-1 benzenesufonyl hydrazide 
• 369-57-3 benzenediazonium tetrafluoroborate 
• 1212-08-4 S-Phenyl benzenethiosulfonate 
• 873-55-2 sodium benzenesulfonate 
• 5183-78-8 methyl(phenylsulfonyl)amide 
• 108-88-3 toluene 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 
• 42060-39-9 N-methyl-N-benzyl-o-nitrobenzenesulfonamide 
• 42060-32-2 N-benzyl-2-nitrobenzenesulfonamide 
• 622-29-7 N-Benzylidenemethylamine 

Downstream Products

• 103-67-3 benzyl-methyl-amine 
• 5183-78-8 methyl(phenylsulfonyl)amide 
• 42060-54-8 6-methyl-6,7-dihydro-5-thia-6-aza-dibenzo[a,c]cycloheptene-5,5-dioxide 
• 65-85-0 benzoic acid 
• 98-11-3 benzenesulfonic acid 

Relevant articles and documents

AEROBIC OXIDATIVE SYNTHESIS OF SULFONAMIDE USING Cu CATALYST

The present invention relates to a method for oxidative synthesis of sulfonamides using copper catalysts. , Oxygen (O) is used. 2 The oxidative synthesis of sulfonamides (1) comprises reacting a 2 th or sulfonyl hydrazide primary amine with a sulfonyl hydrazide (sulfonamide) with a copper catalyst on a solvent under the conditions in which the sulphonamide is fed. The oxidation coupling of the present invention showed extensive substrate ranges in an amine comprising a 2 primary amine, 1 primary amine and amine hydrochloride salt. It is worth notable that non-reactive aliphatic sulfonyl hydrazides in previously reported anaerobic systems can be used for the aerobic oxidation coupling of the present invention. The oxidation coupling of the present invention has been more effective on large scale.

Cu-catalyzed aerobic oxidative synthesis of sulfonamides from sulfonyl hydrazides and amines

An environmentally friendly route for sulfonamides has been developed. The oxidative coupling of sulfonyl hydrazides and amines was catalyzed by CuBr2 to produce various sulfonamides with the water and nitrogen gas as byproducts. Preliminary experiments revealed that the sulfonyl radical is likely to be involved in the reaction mechanism.

A Route to O-Aminosulfonates and Sulfonamides through Insertion of Sulfur Dioxide and Hydrogen Atom Transfer

A three-component reaction of aryldiazonium tetrafluoroborates, the 1,4-diazabicyclo[2.2.2]octane?bis(sulfur dioxide) adduct [DABCO?(SO2)2] and hydroxylamines under catalyst-free and additive-free conditions has been developed, providing aryl O-aminosulfonates in good yields. Sulfonamides could also be obtained via a one-pot process through the reaction of aryldiazonium tetrafluoroborates, DABCO?(SO2)2 and amines in the presence of N-hydroxybenzotriazole. A mechanism involving the insertion of sulfur dioxide and hydrogen atom transfer is proposed and supported by theoretical calculations. (Figure presented.).