42070-90-6

Basic information

• Product Name: (R)-1-(2-Methylphenyl)ethyl alcohol
• Synonyms: (R)-1-(2-Methylphenyl)ethyl alcohol;(R)-(+)-1-(2-Methylphenyl)-1-ethanol;(R)-1-(2-Methylphenyl)ethanol;(R)-1-(2-Tolyl)ethanol;(R)-1-(2-tolyphenyl)ethanol;(R)-1-(o-tolyl)ethan-1-ol
• CAS NO: 42070-90-6
• Molecular Formula: C₉H₁₂O
• Molecular Weight: 136.19098
• EINECS: -0
• Mol File: 42070-90-6.mol
• Article Data: 324

Chemical Properties

• Boiling Point: 216℃
• Flash Point: 104℃
• Appearance: /
• Density: 0.995
• CAS DataBase Reference: (R)-1-(2-Methylphenyl)ethyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(2-Methylphenyl)ethyl alcohol(42070-90-6)
• EPA Substance Registry System: (R)-1-(2-Methylphenyl)ethyl alcohol(42070-90-6)

Safety Data

• Hazardous Substances Data: 42070-90-6(Hazardous Substances Data)

Usage

General Description

(R)-1-(2-Methylphenyl)ethyl alcohol is a chemical compound with the molecular formula C9H12O. It is also known as (R)-(+)-2-Methyl-1-phenylethanol or 2-Methyl-1-phenylethanol. This colorless liquid has a floral, fruity odor and is commonly used as a flavoring agent in the food and beverage industry. It is also used in the production of perfumes and other fragrances. Additionally, it has antimicrobial properties, making it useful in certain pharmaceutical and cosmetic applications. The compound is chiral, meaning it has two non-superimposable mirror image forms, and the (R) configuration is the specific stereochemistry of this compound.

Upstream product

• 108-22-5 Isopropenyl acetate 
• 7287-82-3 1-O-tolyl-ethanol 
• 2371-70-2 tetramethyl titanium 
• 529-20-4 2-methylphenyl aldehyde 
• 577-16-2 2-Methylacetophenone 
• 544-97-8 dimethyl zinc(II) 
• 611-14-3 2-Ethyltoluene 
• 59790-53-3 trimethyl[1-(2-methylphenyl)vinyloxy]silane 
• 766-47-2 1-ethynyl-2-methylbenzene 
• 123-62-6 propionic acid anhydride 
• 75-16-1 methylmagnesium bromide 
• 117-34-0 2,2-diphenylacetic acid 
• 917-54-4 methyllithium 
• 67-63-0 isopropyl alcohol 

Downstream Products

• 1240815-57-9 (S)-(-)-1-(2-methylphenyl)ethyl N,N-diisopropylcarbamate 
• 7287-82-3 1-O-tolyl-ethanol 

Relevant articles and documents

First substoichiometric version of the catalytic enantioselective addition of an alkyllithium to an aldehyde

A substoichiometric enantioselective version of the extremely fast nucleophilic addition of Alk-Li to RCHO is made possible thanks to a thorough analysis of the aggregation phenomena involved in the reaction: calculated quantities of LiCl must be added to

Cinchona-Alkaloid-Derived NNP Ligand for Iridium-Catalyzed Asymmetric Hydrogenation of Ketones

Most ligands applied for asymmetric hydrogenation are synthesized via multistep reactions with expensive chemical reagents. Herein, a series of novel and easily accessed cinchona-alkaloid-based NNP ligands have been developed in two steps. By combining [Ir(COD)Cl]2, 39 ketones including aromatic, heteroaryl, and alkyl ketones have been hydrogenated, all affording valuable chiral alcohols with 96.0-99.9% ee. A plausible reaction mechanism was discussed by NMR, HRMS, and DFT, and an activating model involving trihydride was verified.

PQXdpap: Helical Poly(quinoxaline-2,3-diyl)s Bearing 4-(Dipropylamino)pyridin-3-yl Pendants as Chirality-Switchable Nucleophilic Catalysts for the Kinetic Resolution of Secondary Alcohols

Helically chiral poly(quinoxaline-2,3-diyl)s bearing 4-(dipropylamino)pyridin-3-yl pendants at the 5-position of the quinoxaline ring (PQXdpap) exhibited high catalytic activities and moderate to high selectivities (up to s = 87) in the acylative kinetic resolution of secondary alcohols. The solvent-dependent helical chirality switching of PQXdpap between pure toluene and a 1:1 mixture of toluene and 1,1,2-trichloroethane enabled the preparation of either compound of a pair of enantiomerically pure alcohols (>99% ee) from a single catalyst.