42123-24-0Relevant articles and documents
Comprehensive Synthetic Route to Eight Diastereomeric Podophyllum Lignans
Forsey, Steven P.,Rajapaksa, Dayananda,Taylor, Nicholas J.,Rodrigo, Russell
, p. 4280 - 4290 (2007/10/02)
An oxabicyclo compound, 9, prepared in 47percent yield through an isobenzofuran intermediate was converted with excellent regio- and stereocontrol to eight (+/-)-lignan lactones of the podophyllotoxin series.One of the eight, epiisopicropodophyllin, 36, t
An Efficient Synthesis of Naphthalenic Lignan Lactones
Gokhale, S. M.,Joshi, R. R.,Narasimhan, N. S.
, p. 1030 - 1034 (2007/10/02)
Phthalides (1a-c) have been converted into the corresponding naphthalenic diesters (3a-c) and anhydrides (11, 15) through silyloxyisobenzofurans (2a-c), generated in situ, by reaction with respective dienophiles.The naphthalenic lignan lactones (4a-c), in
Potential Isobenzofurans: their Use in the Synthesis of Naturally Occurring 1-Arylnaphthalide Lignans
Plaumann, Heinz P.,Smith, James G.,Rodrigo, Russell
, p. 354 - 355 (2007/10/02)
A three-step synthesis of seven lignans by means of a Diels-Alder reaction followed by selective borane reduction of an aromatic ester is described.