42221-49-8 Usage
Description
2,4,5-Trichlorobenzoyl chloride is an organic compound with the molecular formula C7H3Cl3O2. It is a derivative of benzoyl chloride, featuring three chlorine atoms at the 2nd, 4th, and 5th positions on the benzene ring. 2,4,5-Trichlorobenzoyl chloride is known for its reactivity and is commonly utilized as a synthetic intermediate in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
2,4,5-Trichlorobenzoyl chloride is used as a synthetic intermediate for the preparation of quinazolines, which act as MCH (melanin-concentrating hormone) receptor antagonists. These antagonists are beneficial in the treatment of various conditions, including improving memory function, regulating sleeping and arousal, managing anxiety, depression, mood disorders, and seizures.
Additionally, 2,4,5-Trichlorobenzoyl chloride serves as an intermediate in the synthesis of 6-Chloro-6-defluoro Ciprofloxacin (C368035), which is an impurity of Ciprofloxacin (C482500). Ciprofloxacin is a fluorinated quinolone antibacterial agent widely used to treat bacterial infections. The synthesis of this intermediate contributes to the development and production of effective antibiotics in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 42221-49-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,2,2 and 1 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 42221-49:
(7*4)+(6*2)+(5*2)+(4*2)+(3*1)+(2*4)+(1*9)=78
78 % 10 = 8
So 42221-49-8 is a valid CAS Registry Number.