4224-63-9Relevant articles and documents
Expedient synthesis of long-chain ω-substituted fatty acids and esters from cyclic ketones using iodine and hydrogen peroxide
Podrezova, Ekaterina V.,Larkina, Maria S.,Belousov, Mikhail V.,Kirschning, Andreas,Zhdankin, Viktor V.,Yusubov, Mekhman S.
, p. 4081 - 4088 (2018/10/15)
A simple and convenient synthesis of ω-iodoaliphatic carboxylic acids and esters by the reaction of cyclic ketones with iodine and hydrogen peroxide in the presence of catalytic CuCl has been developed. ω-Iodoaliphatic carboxylic esters were further used for the efficient preparation of di(2-pyridylmethylamino)alkanoic acids in excellent yields.