42247-75-6

Basic information

• Product Name: Benzoic acid, 2-(2-hydroxyethyl)-
• CAS NO: 42247-75-6
• Molecular Formula: C9H10O3
• Molecular Weight: 166.177
• Mol File: 42247-75-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-(2-hydroxyethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-(2-hydroxyethyl)-(42247-75-6)
• EPA Substance Registry System: Benzoic acid, 2-(2-hydroxyethyl)-(42247-75-6)

Safety Data

• Hazardous Substances Data: 42247-75-6(Hazardous Substances Data)

Upstream product

• 4702-34-5 isochroman-1-one 
• 493-05-0 isochromane 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 10544-72-6 dinitrogen tetraoxide 
• 64-19-7 acetic acid 

Downstream Products

• 1417739-43-5 methyl 4-(N,N-dipropylsulfamoyl)benzoate 
• 1176904-62-3 methyl 2-(2-(tosyloxy)ethyl)benzoate 
• 25109-86-8 methyl 2-(2-bromoethyl)benzoate 
• 1451261-98-5 methyl 2-(2-(4-chloro-2-nitrophenoxy)ethyl)benzoate 
• 1451261-99-6 methyl 2-(2-(2-amino-4-chlorophenoxy)ethyl)benzoate 
• 1451261-84-9 methyl 2-(2-{2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chlorophenoxy}ethyl)benzoate 
• 1451261-85-0 2-(2-{2-[(1-benzofuran-2-ylsulfonyl)amino]-4-chlorophenoxy}ethyl)benzoic acid 
• 888324-99-0 6-(2-((tert-butyldimethylsilyloxy)methyl)phenyl)-4-((4-methoxybenzyloxy)methyl)-2-(tert-butyldimethylsilyloxy)hex-1-en 
• 888324-98-9 6-(2-((tert-butyldimethylsilyloxy)methyl)phenyl)-4-((4-methoxybenzyloxy)methyl)hex-1-en-3-ol 
• 888324-78-5 diethyl 2-(2-((tert-butyldimethylsilyloxy)methyl)phenethyl)-3-oxopentanedioate 
• 888325-00-6 3-(tert-butyldimethylsilyloxy)-2-{2-[2-(tert-butyldimethylsilyloxymethyl)phenyl]ethyl}pent-4-en-1-ol 
• 888324-97-8 4-(2-((tert-butyldimethylsilyloxy)methyl)phenyl)-2-((4-methoxybenzyloxy)methyl)butan-1-ol 
• 888325-03-9 Se-phenyl 2-[4-(tert-butyldimethylsilyloxy)-3-vinylhex-5-enyl]benzoselenoate 
• 888325-01-7 1-(tert-butyldimethylsilyloxymethyl)-2-[4-(tert-butyldimethylsilyloxy)-3-vinylhex-5-enyl]benzene 

Relevant articles and documents

A chloroacetate based ratiometric fluorescent probe for cysteine detection in biosystems

The specific detection of cysteine (Cys) over homocysteine (Hcy), glutathione (GSH) and other amino acids is of great significance for studying its biological functions as well as for the diagnosis of related diseases. Chloroacetyl group was often used as a reaction site for cysteine fluorescent probes for its sensitivity and selectivity. However, high background fluorescence and low stability are common problems encountered by such probes. Here, four chloroacetyl group based fluorescent probes (C1, C2, C3, and H4) was synthesized for a comparative study. We found that the inefficient quenching ability of chloroacetyl group turned into an advantage when connected with a ratiometric fluorophore. With the modification of chloroacetyl group, probe H4 displayed excellent ratiometric property and great selectivity for Cys, the stability was also improved. Additionally, the probe was successfully applied for quantitative detection of Cys in fetal bovine serum and real-time imaging in living HeLa cells with low toxicity.

Functionalized esters as bis-electrophiles in a silicon-induced domino synthesis of annulated carbocycles

The reaction of silyl-substituted carbanion 1b with arene-1,2-dicarboxylates 6, 15 yields indenone derivatives 11, 16 in a domino process involving silyl C→O migration and elimination. However, in a competing pathway, the initial addition of 1b leads to l

Proximately Assisted and Chemoselectively Cleavable Protecting Groups for Alcohols, 2-benzoic Esters

Alcohols were protected by esterification with new protecting reagents, 2-benzoic acids and the esters were chemoselectively deprotected in a proximately assisted manner even in the presence of acetyl, levulinyl, and silyl groups.