422556-08-9

Basic information

• Product Name: PYROXSULAM
• Synonyms: PYROXSULAM;Pyroxsulam [iso];N-(5,7-Dimethoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)-3-pyridinesulfonamide;3-Pyridinesulfonamide,N-(5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)-
• CAS NO: 422556-08-9
• Molecular Formula: C₁₄H₁₃F₃N₆O₅S
• Molecular Weight: 434.354
• Mol File: 422556-08-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.68
• Refractive Index: 1.633
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 1.92±0.30(Predicted)
• CAS DataBase Reference: PYROXSULAM(CAS DataBase Reference)
• NIST Chemistry Reference: PYROXSULAM(422556-08-9)
• EPA Substance Registry System: PYROXSULAM(422556-08-9)

Safety Data

• Hazardous Substances Data: 422556-08-9(Hazardous Substances Data)

Usage

Uses

Pyroxsulam is a herbicide containing auxin hormone and two acetolactate synthase inhibitors for controlling weeds.

InChI:InChI=1/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)

Upstream product

• 13223-43-3 5,7-dimethoxy-[1,2,4]-triazolo-[1,5-a]-pyrimidin-2-amine 
• 219715-41-0 2-methoxy-4-(trifluoromethyl)-pyridine-3-sulfonyl chloride 

Relevant articles and documents

CRYSTALLINE FORMS OF N-(5,7-DIMETHOXY-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YL)-2-METHOXY-4-(TRIFLUOROMETHYL)PYRIDINE-3-SULFONAMIDE

The present invention relates to novel crystalline forms of N-(5,7-dimethoxy- [1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide (pyroxsulam) A-G, to processes for their preparation, mixtures and compositions comprising them and to the methods of using said crystals and said compositions as pesticidal agents for treating crops and plants.

Application of the tisler triazolopyrimidine cyclization to the synthesis of a crop protection agent and an intermediate

A new synthetic route to the Dow AgroSciences early stage sulfonamide herbicide 3-(2-methoxy-4-trifluoromethyl)-N-(5,7-dimethoxy[1,2,4]triazolo[1,5-a] pyrimidin-2-yl)pyridinesulfonamide (pyroxsulam) has been developed. The synthesis is based on formation of the triazole ring as the final step, utilizing the Tisler triazolopyrimidine cyclization. A Tisler cyclization route to 2-amino-5,7-dimethoxy-1,2,4-trazolo[1,5-a]pyrimidine starting with 2-chloro-4,6-dimethoxypyrimidine has also been demonstrated.