42307-60-8

Basic information

• Product Name: Benzeneacetaldehyde, a-ethyl-, (R)-
• CAS NO: 42307-60-8
• Molecular Formula: C10H12O
• Molecular Weight: 148.205
• Mol File: 42307-60-8.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzeneacetaldehyde, a-ethyl-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetaldehyde, a-ethyl-, (R)-(42307-60-8)
• EPA Substance Registry System: Benzeneacetaldehyde, a-ethyl-, (R)-(42307-60-8)

Safety Data

• Hazardous Substances Data: 42307-60-8(Hazardous Substances Data)

Upstream product

• 873-66-5 1-propenylbenzene 
• 201230-82-2 carbon monoxide 
• 766-90-5 cis-1-phenyl-1-propylene 
• 7217-71-2 1-phenyl-2-propenyl acetate 
• 100-52-7 benzaldehyde 
• 444575-79-5 carbonic acid 1,1-dimethylethyl 1-phenyl-2-propenyl ester 
• 2294-71-5 (-)-(R)-2-phenyl-butyric acid methyl ester 
• 90-27-7 2-Phenylbutyric acid 
• 2245-25-2 2-phenyl-1,2-epoxybutane 
• 103-80-0 phenylacetyl chloride 
• 159213-05-5 pseudoephedrine benzeneacetamide 
• 201005-62-1 (4R,E)-4-ethyl-2-(2-phenylethenyl)-4,5-dihydro-1,3-oxazole 
• 675855-18-2 (4R)-4-ethyl-2-[(2S,E)-2-phenyl-3-decenyl]-4,5-dihydro-1,3-oxazole 
• 4513-94-4 1H-pyrrole-2-carbonitrile 

Downstream Products

• 16460-75-6 (R)-2-phenyl-butan-1-ol 
• 106268-80-8 (4R,5R)-5-phenyl-1-hepten-4-ol 
• 106268-79-5 (4S,5R)-5-phenyl-1-hepten-4-ol 

Relevant articles and documents

1,1-Diborylalkyl-1-Metal Compounds, Preparation Method Thereof, and Their Applications Toward Synthesis of 1,1-Diboronate Ester Compounds

The present invention relates to a 1,1-diborylalkyl-1-metal compound including one metal group together with two identical boron groups at the sp3 carbon center, and its use. Specifically, the present invention relates to development of novel organic reactions, synthesis of functional molecules, and synthesis of new drugs by applying the novel 1,1-diboryl-1-metal substituted alkyl compounds to various molecular libraries which could not be synthesized by conventional methodologies.

Enantioselective Copper-Catalyzed Defluoroalkylation Using Arylboronate-Activated Alkyl Grignard Reagents

A copper-catalyzed system has been introduced for the enantioselective defluoroalkylation of linear 1-(trifluoromethyl)alkenes through C-F activation to synthesize various gem-difluoroalkenes as carbonyl mimics. For the first time, arylboronate-activated alkyl Grignard reagents were uncovered in this cross-coupling reaction. Mechanistic studies confirmed that the tetraorganoborate complexes generated in situ were the key reactive species for this transformation.

Rhodium/tris-binaphthyl chiral monophosphite complexes: Efficient catalysts for the hydroformylation of disubstituted aryl olefins

A family of threefold symmetry phosphite ligands, P(O-BIN-OR)3 (BIN = 2,2′-binaphthyl; R = Me, Bn, CHPh2, 1-adamantyl), derived from enantiomerically pure (R)-BINOL, was developed. Cone angles within the range 240-270° were calculated for the phosphite ligands, using the computational PM6 Hamiltonian. Their rhodium complexes formed in situ showed remarkable catalytic activity in the hydroformylation of hindered phenylpropenes, under relatively mild reaction conditions, with full chemoselectivity for aldehydes, high regioselectivity, however with low enantioselectivity. The ether substituents at the ligand affected considerably the catalytic activity on the hydroformylation of 1,1- and 1,2-disubstituted aryl olefins. The kinetics of the hydroformylation of trans-1-phenyl-1-propene, using tris[(R)-2′-benzyloxy-1,1′-binaphthyl-2-yl]phosphite as model ligand, was investigated. A first order dependence in the hydroformylation initial rate with respect to substrate and catalyst concentrations was found, as well as a positive order with respect to the partial pressure of H2, and a slightly negative order with respect to phosphite concentration and CO partial pressure.