423172-83-2

Basic information

• Product Name: 4-bromo-3-[4-(1-[1,3]dioxolan-2-ylmethyl-1H-indol-3-yl)-piperidin-1-ylmethyl]-benzoic acid
• CAS NO: 423172-83-2
• Molecular Weight: 499.404
• Mol File: 423172-83-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-bromo-3-[4-(1-[1,3]dioxolan-2-ylmethyl-1H-indol-3-yl)-piperidin-1-ylmethyl]-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-3-[4-(1-[1,3]dioxolan-2-ylmethyl-1H-indol-3-yl)-piperidin-1-ylmethyl]-benzoic acid(423172-83-2)
• EPA Substance Registry System: 4-bromo-3-[4-(1-[1,3]dioxolan-2-ylmethyl-1H-indol-3-yl)-piperidin-1-ylmethyl]-benzoic acid(423172-83-2)

Safety Data

• Hazardous Substances Data: 423172-83-2(Hazardous Substances Data)

Upstream product

• 4360-63-8 2-bromomethyl-1,3-dioxolane 
• 423173-97-1 4-bromo-3-[4-(1H-indol-3-yl)-piperidin-1-ylmethyl]-benzoic Acid Methyl Ester 

Relevant articles and documents

INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS

The invention relates to indolyl piperidinyl derivatives of formula (I) wherein: A1 represents an alkylene, alkyleneoxy, alkylenethio, alkanoylene or hydroxyalkylene group; A2 represents an alkylene, alkyleneoxy, alkylenethio, alkanoylene or an alkyleneoxyalkylene group; W1 represents a phenylene, furanylene or pyridinylene group which is unsubstituted or substituted by one or more halogen atoms, alkoxy groups and/or alkyl groups; W2 represents a 3-10 membered monocyclic or bicyclic group containing from 1 to 3 heteroatoms said group being unsubstituted or substituted by one or more halogen atoms, alkyl groups, alkoxy groups and/or oxo groups; R1 represents a hydrogen or halogen atom or an alkyl, alkoxy or methylamino group; and R2 represents a carboxyl group; and pharmaceutically acceptable salts thereof; to processes for their preparation; to pharmaceutical compositions containing them; and to their medical use as antihistaminic and antiallergic agents.