42413-59-2

Basic information

• Product Name: 1-(4-Chlorophenyl)-1-phenylacetone
• Synonyms: 1-(4-Chlorophenyl)-1-phenylacetone;1-(4-Chlorophenyl)-1-phenylpropan-2-one;1-PHENYL-1-P-CHLORO PHENYL ACETONE;1-(4-Chlorophenyl)-1-phenyl-2-propanone
• CAS NO: 42413-59-2
• Molecular Formula: C₁₅H₁₃ClO
• Molecular Weight: 244.72
• EINECS: 255-813-5
• Mol File: 42413-59-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 341.4 °C at 760 mmHg
• Flash Point: 198.5 °C
• Appearance: /
• Density: 1.156 g/cm³
• Vapor Pressure: 8.04E-05mmHg at 25°C
• Refractive Index: 1.573
• CAS DataBase Reference: 1-(4-Chlorophenyl)-1-phenylacetone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Chlorophenyl)-1-phenylacetone(42413-59-2)
• EPA Substance Registry System: 1-(4-Chlorophenyl)-1-phenylacetone(42413-59-2)

Safety Data

• Hazardous Substances Data: 42413-59-2(Hazardous Substances Data)

Usage

General Description

1-(4-Chlorophenyl)-1-phenylacetone, also known as 4'-Chloroacetophenone, is a chemical compound with the formula C16H13ClO. It is a white solid with a strong, sweet odor, and it is commonly used in the synthesis of pharmaceuticals and other organic compounds. 1-(4-Chlorophenyl)-1-phenylacetone is known for its use in the production of amphetamines and other stimulant drugs. It is also used in the production of various perfumes and fragrances due to its distinct odor. Additionally, 1-(4-Chlorophenyl)-1-phenylacetone has applications in the field of organic chemistry and is used as a reagent in various chemical reactions. However,

InChI:InChI=1/C15H13ClO/c1-11(17)15(12-5-3-2-4-6-12)13-7-9-14(16)10-8-13/h2-10,15H,1H3

Upstream product

• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 71-43-2 benzene 
• 108-90-7 chlorobenzene 
• 872818-20-7 1-(4-chloro-phenyl)-1-phenyl-propane-1,2-diol 

Downstream Products

• 101018-31-9 1-(4-chlorophenyl)-1-phenylprop-2-en-1-ol 
• 1042964-73-7 3-(4-chlorophenyl)-2-methyl-3-phenylprop-1-ene-1,1-dicarbonitrile 
• 3691-35-8 chlorophacinone 

Relevant articles and documents

Anodic oxidation triggered divergent 1,2- And 1,4-group transfer reactions of β-hydroxycarboxylic acids enabled by electrochemical regulation

We report a set of electrochemically regulated protocols for the divergent synthesis of ketones and β-keto esters from the same β-hydroxycarboxylic acid starting materials. Enabled by electrochemical control, the anodic oxidation of carboxylic acids proceeded in either a one-electron or a two-electron pathway, leading to a 1,4-aryl transfer or a semipinacol-type 1,2-group transfer product with excellent chemoselectivity. The 1,4-aryl transfer represents an unprecedented example of carbon-to-oxygen group transfer proceeding via a radical mechanism. In contrast to previously reported radical group transfer reactions, this 1,4-group transfer process features the migration of electron-rich aryl substituents. Furthermore, with these chemoselective electrochemical oxidation protocols, a range of ketones and β-keto esters including those possessing a challenging-to-access medium-sized ring could be synthesized in excellent yields. This journal is