42427-51-0

Basic information

• Product Name: Benzene, 1-bromo-4-(1-methylenepropyl)-
• CAS NO: 42427-51-0
• Molecular Formula: C10H11Br
• Molecular Weight: 211.101
• Mol File: 42427-51-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzene, 1-bromo-4-(1-methylenepropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-bromo-4-(1-methylenepropyl)-(42427-51-0)
• EPA Substance Registry System: Benzene, 1-bromo-4-(1-methylenepropyl)-(42427-51-0)

Safety Data

• Hazardous Substances Data: 42427-51-0(Hazardous Substances Data)

Upstream product

• 10342-83-3 4'-Bromopropiophenone 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 75-11-6 diiodomethane 

Downstream Products

• 848893-61-8 p-bromo-α,β-dimethylstyrene 
• 1638238-87-5 4-(4-bromophenyl)-6-phenyl-1-tosyl-2,5-dihydro-1H-azepine 
• 51431-71-1 1-Bromo-4-(2,2-dichloro-1-ethyl-cyclopropyl)-benzene 

Relevant articles and documents

Electrochemical fluorosulfonylation of alkenes to access vicinal fluorinated sulfones derivatives

Herein, we report a practical and efficient fluorosulfonylation of the various alkenes with sulfonyl radical sources (RSO2NHNH2) and Et3N·3HF as cost-effective fluorination reagents under mild conditions. Remarkably, this

Cobalt(II)-Catalyzed Stereoselective Olefin Isomerization: Facile Access to Acyclic Trisubstituted Alkenes

Stereoselective synthesis of trisubstituted alkenes is a long-standing challenge in organic chemistry, due to the small energy differences between E and Z isomers of trisubstituted alkenes (compared with 1,2-disubstituted alkenes). Transition metal-catalyzed isomerization of 1,1-disubstituted alkenes can serve as an alternative approach to trisubstituted alkenes, but it remains underdeveloped owing to issues relating to reaction efficiency and stereoselectivity. Here we show that a novel cobalt catalyst can overcome these challenges to provide an efficient and stereoselective access to a broad range of trisubstituted alkenes. This protocol is compatible with both mono- and dienes and exhibits a good functional group tolerance and scalability. Moreover, it has proven to be a useful tool to construct organic luminophores and a deuterated trisubstituted alkene. A preliminary study of the mechanism suggests that a cobalt-hydride pathway is involved in the reaction. The high stereoselectivity of the reaction is attributed to both a π-πstacking effect and the steric hindrance between substrate and catalyst.