42497-80-3

Basic information

• Product Name: Benzoic acid, 4-(phenylethynyl)-, methyl ester
• CAS NO: 42497-80-3
• Molecular Formula: C16H12O2
• Molecular Weight: 236.27
• Mol File: 42497-80-3.mol
• Article Data: 111

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-(phenylethynyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(phenylethynyl)-, methyl ester(42497-80-3)
• EPA Substance Registry System: Benzoic acid, 4-(phenylethynyl)-, methyl ester(42497-80-3)

Safety Data

• Hazardous Substances Data: 42497-80-3(Hazardous Substances Data)

Upstream product

• 1126-46-1 Methyl 4-chlorobenzoate 
• 536-74-3 phenylacetylene 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 637-44-5 phenylpropyolic acid 
• 619-44-3 methyl 4-iodobenzoate 
• 108-86-1 bromobenzene 
• 13984-49-1 (phenylethynyl)zinc chloride 
• 66737-07-3 1-(4-methoxycarbonylphenyl)-3-phenylpropynone 
• 1357155-90-8 3-((4-methoxycarbonyl)phenyl) propiolic acid 
• 80-17-1 benzenesufonyl hydrazide 
• 591-50-4 iodobenzene 
• 90965-06-3 dimethyl 1-(1-diazo-2-oxopropyl)phosphonate 
• 1571-08-0 methyl 4-formylbenzoate 
• 709-69-3 methyl 4-(fluorocarbonyl) benzoate 

Downstream Products

• 1149-18-4 (E)-methyl 4-styrylbenzoate 
• 1171122-83-0 methyl 4-(3-phenyl-1H-indol-2-yl)benzoate 
• 93503-74-3 4-(2-phenyl-1H-indol-3-yl)benzoic acid methyl ester 
• 54737-75-6 (4-(phenylethynyl)phenyl)methanol 
• 101093-37-2 4-(methanol)stilbene 
• 34224-29-8 (4-phenethylphenyl)methanol 
• 94161-45-2 methyl 4-(2-oxo-2-phenylethyl)benzoate 
• 143886-45-7 benzyl 4-methoxycarbonylphenyl ketone 

Relevant articles and documents

Mechanistic study of palladium-catalyzed decarboxylative coupling of phenylpropiolic acid and aryl iodide

The mechanism of decarboxylative coupling of phenylpropiolic acid and methyl 4-iodobenzoate was investigated by gas chromatographic analysis and monitoring the decarboxylation reaction by FT-IR spectroscopy. Among many possible pathways, we found that the

Si-Gly-CD-PdNPs as a hybrid heterogeneous catalyst for environmentally friendly continuous flow Sonogashira cross-coupling

We have reported a waste-minimized protocol for the Sonogashira cross-coupling exploiting the safe use of a CPME/water azeotropic mixture and the utilization of a heterogeneous hybrid palladium catalyst supported onto a silica/β-cyclodextrin matrix in con

Ligand-free (: Z)-selective transfer semihydrogenation of alkynes catalyzed by in situ generated oxidizable copper nanoparticles

Herein, we present (Z)-selective transfer semihydrogenation of alkynes based on in situ generated CuNPs in the presence of hydrogen donors, such as ammonia-borane and a green protic solvent. This environmentally friendly method is characterized by operational simplicity combined with high stereo- and chemoselectivity and functional group compatibility. Auto-oxidation of CuNPs after the completion of a semihydrogenation reaction results in the formation of a water-soluble ammonia complex, so that the catalyst may be reused several times by simple phase-separation with no need for any special regeneration processes. Formed NH4B(OR)4 can be easily transformed back into ammonia-borane or into boric acid. In addition, a one-pot tandem sequence involving a Suzuki reaction followed by semihydrogenation was presented, which allows minimization of chemical waste production.