4252-61-3Relevant articles and documents
Aryl group - A leaving group in arylphosphine oxides
Stankevi?, Marek,Pisklak, Jolanta,W?odarczyk, Katarzyna
, p. 810 - 824 (2016/01/20)
The treatment of triphenylphosphine oxide with organometallic reagents leads to the substitution of up to three phenyl substituents with the incoming carbon nucleophile. The replacement of the phenyl/aryl group in tertiary diarylalkylphosphine oxides or even aryldialkylphosphine oxides was also observed. Naphthyl-substituted phosphine oxides undergo Michael-type addition at the naphthyl group when treated with organolithium reagent.
Synthesis of phosphane oxides and phosphonates by cerium-mediated addition of organolithium compounds to chloro-phosphorus compounds
Dalpozzo, Renato,De Nino, Antonio,Miele, Daniela,Tagarelli, Antonio,Bartoli, Giuseppe
, p. 2299 - 2301 (2007/10/03)
The addition of organocerium reagents 2a-g to phosphinoyl chloride 1a or chlorophosphates 1b leads to the synthesis of phosphane oxides 3aa-ag and phosphonates 3bb, be in good to high yield. The reaction can be extended to cerium enolates 4 (of ketones) and 6 (of nitriles) except when a benzyl group bound to the carbonyl moiety should be metallated. The latter reaction is the first reported synthesis of β-oxophosphane oxides by a simple reaction between enolates and a phosphorus(V) halide.
Novel Direct Deoxygenation of the Hydroxy Group of (1-Hydroxyalkyl)-diphenylphosphine Oxides
Yamashita, Mitsuji,Suzuki, Takanobu,Imoto, Hiroyuki,Oshikawa, Tatsuo,Inokawa, Saburo
, p. 556 - 557 (2007/10/02)
The hydroxyl group of (1-hydroxyalkyl)-diphenylphosphine oxides 1 is directly deoxygenated on treatment with phosphorus trichloride and iodides to give parent alkyl-diphenylphosphine oxides 2.
