42542-57-4

Basic information

• Product Name: 2,4(1H,3H)-Pyrimidinedione, 1-methyl-6-phenyl-
• Synonyms: 1-methyl-6-phenyl-1H-pyrimidine-2,4-dione;1-Methyl-6-phenyl-1H-pyrimidin-2,4-dion;1-methyl-6-phenyluracil;1-N-Methyl-6-Phenyl-2,4Pyrimidine-Dione
• CAS NO: 42542-57-4
• Molecular Formula: C11H10N2O2
• Molecular Weight: 202.20900
• Mol File: 42542-57-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, 1-methyl-6-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, 1-methyl-6-phenyl-(42542-57-4)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 1-methyl-6-phenyl-(42542-57-4)

Safety Data

• Hazardous Substances Data: 42542-57-4(Hazardous Substances Data)

Upstream product

• 107-06-2 1,2-dichloro-ethane 
• 31737-09-4 6-chloro-1-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 
• 98-80-6 phenylboronic acid 
• 55323-83-6 6-phenyl-2H-3,4-dihydro-1,3-oxazine-2,4-dione 
• 36822-11-4 6-phenyl-2-thiouracil 
• 96121-14-1 2-amino-6-phenyl-1,3-oxazin-4-one 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 74-89-5 methylamine 
• 102649-61-6 2-(methylthio)-1-methyl-6-phenyl-4(3H)-pyrimidinone 

Downstream Products

• 86762-40-5 1-methyl-6-phenyl-dihydro-pyrimidine-2,4-dione 

Relevant articles and documents

PYRIMIDONE COMPOUNDS USED AS LP-PLA2 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS THEREOF

The present invention relates to pyrimidone compounds used as Lp-PLA2 inhibitors and pharmaceutical compositions thereof. The structure of the pyrimidone compounds is represented by general formula (I), wherein R1, R2, Rs

Pyrimidinones. 3. N-substituted 6-phenylpyrimidinones and pyrimidinediones with diuretic/hypotensive and antiinflammatory activity

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REGIOSPECIFIC SYNTHESIS OF N-1 AND N-2 SUBSTITUTED PYRIMIDONES EMPLOYING A NOVEL 1,3-OXAZINE PREPARATION

Reaction of ethyl benzoylacetate with methylthiopseudourea resulted in expulsion of methylmercaptan to afford 2-amino-6-phenyl-4H-1,3-oxazin-4-one in good yield.This novel oxazine synthesis was exploited to secure N-1 and N-2 substituted pyrimidinones regiospecifically.