425431-08-9Relevant articles and documents
A strategy for the construction of caged diols using a photolabile protecting group
Lin, Weiying,Lawrence, David S.
, p. 2723 - 2726 (2007/10/03)
Caged analogues of biologically active compounds have received widespread attention as temporally and spatially controlled probes of cell-based processes. Recently, a coumarin-4-ylmethyl derivative has been used to cage carboxylates, sulfonates, carbamates, and phosphates. We describe herein a synthetic strategy that furnishes photosensitive caged diols and provides an entry into the protection/photodeprotection of functionality with modest leaving group abilities.