425666-39-3

Basic information

• Product Name: N-(5-chloro-2-methoxyphenyl)-4-{[(3,4-dimethylphenyl)(methylsulfonyl)amino]methyl}benzamide
• Synonyms: N-(5-chloro-2-methoxyphenyl)-4-{[(3,4-dimethylphenyl)(methylsulfonyl)amino]methyl}benzamide
• CAS NO: 425666-39-3
• Molecular Weight: 472.993
• Mol File: 425666-39-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(5-chloro-2-methoxyphenyl)-4-{[(3,4-dimethylphenyl)(methylsulfonyl)amino]methyl}benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-chloro-2-methoxyphenyl)-4-{[(3,4-dimethylphenyl)(methylsulfonyl)amino]methyl}benzamide(425666-39-3)
• EPA Substance Registry System: N-(5-chloro-2-methoxyphenyl)-4-{[(3,4-dimethylphenyl)(methylsulfonyl)amino]methyl}benzamide(425666-39-3)

Safety Data

• Hazardous Substances Data: 425666-39-3(Hazardous Substances Data)

Upstream product

• 1356853-96-7 N-(4-cyanobenzyl)-N-(3,4-dimethylphenyl)methanesulfonamide 
• 1019540-64-7 4-{[(3,4-dimethylphenyl)amino]methyl}benzonitrile 
• 10272-06-7 3-chloro-5-methoxyaniline 
• 359020-78-3 4-{[(3,4-dimethylphenyl)(methylsulfonyl)amino]methyl}benzoic acid 
• 95-64-7 4-amino-o-xylene 
• 105-07-7 4-cyanobenzaldehyde 

Relevant articles and documents

5-LIPOXYGENASE INHIBITORS

The present invention relates to sulfonamides derivatives as 5-lipoxygenase (5-LO) inhibitors and a process for their synthesis. The present invention also relates to pharmacological compositions containing these sulfonamides derivatives, as well as methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, Type I diabetes, psoriasis, allograft rejection, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis, allergic rhinitis and other inflammatory and/or autoimmune disorders.