4272-77-9Relevant articles and documents
Photolysis of the sulfonamide bond of metal complexes of N-dansyl-1,4,7,10-tetraazacyclododecane in aqueous solution: A mechanistic study and application to the photorepair of cis,syn-cyclobutane thymine photodimer
Aoki, Shin,Tomiyama, Yumiko,Kageyama, Yoshiyuki,Yamada, Yasuyuki,Shiro, Motoo,Kimura, Eiichi
, p. 561 - 573 (2009)
Sulfonamide constitutes a ubiquitous functional group that is frequently used in organic chemistry, analytical chemistry, and medicinal chemistry. We report herein on the photolysis of a dansylamide moiety of 1-dansyl-1,4,7,10- tetraazzacyclododecane (Nda
Synthetic method of dansyl chloride for preparing fluorescent probe (by machine translation)
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Paragraph 0029-0035, (2020/07/14)
The preparation method comprises the following steps: dissolving rhodamine sulfonic acid in an organic solvent to obtain an emulsion; sequentially dropwise adding thionyl chloride and phosphorus pentachloride into the suspension; controlling the temperature of the system to 40 - 45 °C; reacting 4 - 6h; adjusting pH to 5 - 6; and collecting the product to obtain the folic acid chloride. The invention further discloses a fluorescent probe prepared from the dansyl chloride. In the synthesis process of the target fluorescent compound, by adding the phosphorus pentachloride catalyst, the use amount of thionyl chloride is reduced, the reaction condition is mild, and the method can be carried out at a lower temperature. (by machine translation)
Dual signaling of thallium(III) ions via oxidative cleavage of a sulfonhydrazide linkage
Ahn, Sangdoo,Chang, Suk-Kyu,Choi, Myung Gil,Lee, Yu Jeong,Park, Tae Jung,Yoo, Jae Hoon
, (2020/03/17)
The thallium is widely used in various research and industrial applications but is very toxic. In this work, we developed a novel reaction-based dual signaling probe for the selective and sensitive determination of Tl3+ via the oxidative cleavage of a rhodamine–dansylhydrazide conjugate. The designed probe showed pronounced colorimetric and fluorescence signaling behavior toward Tl3+ with a detection limit of 1.3 × 10–7 M (0.027 ppm), as well as selectivity over other common metal ions, anions, and oxidants. The Tl3+ signaling process required less than 2 min and was not influenced by the solution pH within the range of 4.0–5.5; however, the signal diminished significantly above pH 6.0. To demonstrate the practical applicability of the designed probe, a simple and convenient colorimetric assay for the determination of Tl3+ in commercial reagents was established using an office scanner as a readily available signal capturing device.
A trifluoroacetic acid-labile sulfonate protecting group and its use in the synthesis of a near-IR fluorophore
Pauff, Steven M.,Miller, Stephen C.
supporting information, p. 711 - 716 (2013/02/25)
Sulfonated molecules exhibit high water solubility, a property that is valuable for many biological applications but often complicates their synthesis and purification. Here we report a sulfonate protecting group that is resistant to nucleophilic attack but readily removed with trifluoroacetic acid (TFA). The use of this protecting group improved the synthesis of a sulfonated near-IR fluorophore and the mild deprotection conditions allowed isolation of the product without requiring chromatography.
