4277-29-6

Basic information

• Product Name: CYCLOHEPTANECARBALDEHYDE
• Synonyms: CYCLOHEPTANECARBALDEHYDE;CYCLOHEPTANECARBOXALDEHYDE;RARECHEM AK ML 0066;formylcycloheptane
• CAS NO: 4277-29-6
• Molecular Formula: C8H14O
• Molecular Weight: 126.2
• EINECS: 224-279-5
• Mol File: 4277-29-6.mol
• Article Data: 25

Chemical Properties

• Boiling Point: 184 °C at 760 mmHg
• Flash Point: 58.7 °C
• Appearance: /
• Density: 0.965g/cm³
• Vapor Pressure: 0.748mmHg at 25°C
• Refractive Index: 1.506
• CAS DataBase Reference: CYCLOHEPTANECARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: CYCLOHEPTANECARBALDEHYDE(4277-29-6)
• EPA Substance Registry System: CYCLOHEPTANECARBALDEHYDE(4277-29-6)

Safety Data

• Statements: 10-36/37/38
• Safety Statements: 16-26-36/37/39
• RIDADR: 1989
• Hazardous Substances Data: 4277-29-6(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 87, p. 1353, 1965 DOI: 10.1021/ja01084a034

InChI:InChI=1/C8H14O/c9-7-8-5-3-1-2-4-6-8/h7-8H,1-6H2

Upstream product

• 6975-19-5 1-oxa-spiro[2.6]nonane-2-carboxylic acid ethyl ester 
• 931-88-4 cis-Cyclooctene 
• 286-62-4 Cyclooctene oxide 
• 73039-85-7 2-Carbomethoxy-1-oxaspiro<2,6>nonane 
• 74397-19-6 1-(hydroxymethyl)cycloheptanol 
• 95826-90-7 1,3,6-Cycloheptatrien-1-carbaldehyd 
• 99850-74-5 cycloheptanecarbaldehyde dimethylacetal 
• 2453-46-5 cycloheptyl chloride 
• 68-12-2 N,N-dimethyl-formamide 
• 931-89-5 (E)-cyclooctene 
• 64-18-6 formic acid 
• 628-92-2 Cycloheptene 
• 2591-86-8 N-Formylpiperidine 
• 2404-35-5 cycloheptyl bromide 

Downstream Products

• 1279722-90-5 2-(cycloheptylidenemethyl)benzenamine 
• 1279722-98-3 C₁₄H₁₇N₃ 
• 22793-63-1 6,7,8,9,10,11-Hexahydro-5H-cycloocta[b]indole 
• 13705-33-4 cycloheptyl(phenyl)methanol 
• 1460-16-8 cycloheptanoic acid 
• 512177-27-4 4-acetyl-5-cycloheptyl-3-hydroxy-1-(4-methylphenyl)-1,5-dihydro-2H-pyrrol-2-one 
• 3349-73-3 cycloheptanone 2,4-dinitrophenylhydrazone 
• 4448-75-3 cycloheptylmethanol 
• 1098107-83-5 C₁₆H₂₁Cl₃O₃S 

Relevant articles and documents

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The organocatalyzed Mannich coupling of cyclic carboxaldehydes allowed the concise and simple preparation of spirocyclic aminolactones. Their conversion into pharmaceutically relevant spiro[4.5]cyclic and spiro[4.6]cyclic 3-aminopyrrolidines is also described.

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