428874-67-3

Basic information

• Product Name: R-2,2'-bis(methoxymethoxy)-3,3'-diphenyl-1,1'-Binaphthalene
• Synonyms: R-2,2'-bis(methoxymethoxy)-3,3'-diphenyl-1,1'-Binaphthalene;(R)-2,2'-Bis(methoxymethoxy)-3,3'-diphenyl-1,1'- binaphthalene,99%e.e.
• CAS NO: 428874-67-3
• Molecular Formula: C₃₆H₃₀O₄
• Molecular Weight: 526.621
• Mol File: 428874-67-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 582.4±50.0 °C(Predicted)
• Appearance: /
• Density: 1.177±0.06 g/cm3(Predicted)
• CAS DataBase Reference: R-2,2'-bis(methoxymethoxy)-3,3'-diphenyl-1,1'-Binaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: R-2,2'-bis(methoxymethoxy)-3,3'-diphenyl-1,1'-Binaphthalene(428874-67-3)
• EPA Substance Registry System: R-2,2'-bis(methoxymethoxy)-3,3'-diphenyl-1,1'-Binaphthalene(428874-67-3)

Safety Data

• Hazardous Substances Data: 428874-67-3(Hazardous Substances Data)

Usage

General Description

R-2,2'-bis(methoxymethoxy)-3,3'-diphenyl-1,1'-binaphthalene is a synthetic organic compound with a complex chemical structure. It is commonly used as a chiral ligand in asymmetric catalysis, where it plays a key role in facilitating a variety of chemical reactions with high selectivity and efficiency. R-2,2'-bis(methoxymethoxy)-3,3'-diphenyl-1,1'-Binaphthalene is known for its ability to influence the stereochemistry of various reactions, making it a valuable tool in the field of organic synthesis. Additionally, R-2,2'-bis(methoxymethoxy)-3,3'-diphenyl-1,1'-binaphthalene has been studied for its potential applications in medicine, particularly in the development of new pharmaceuticals and biologically active compounds. Overall, this chemical compound has significant importance in both academic research and industrial applications due to its unique properties and versatility.

Upstream product

• 98-80-6 phenylboronic acid 
• 602-09-5 1,1'-bi-2-naphthol 
• 173831-50-0 rac-2,2'-bis-(methoxymethoxy)-1,1'-binaphthalene 
• 142010-87-5 (±)?3,3'?dibromo?2,2'?bis(methoxymethyl)?1,1'?binaphthalene 

Downstream Products

• 75640-70-9 3,3'-diphenyl-1,1'-bi-2-naphthol 

Relevant articles and documents

Synthesis of (±)-3,3′-diphenyl-2,2′-binaphthol via different routes using Pd and Ni as catalyst respectively

3,3′-Biphenyl-2,2′-binaphthols (BINOLs) are precursors of phosphoric acids that are widely used as ligands and catalysts in organic reactions. In this report, two routes for the synthesis of (±)-3,3′-diphenyl BINOLs via (±)-3,3′ bis-halogenated BINOLs int

Design of bronsted acid-assisted chiral Lewis acid (BLA) catalysts for highly enantioselective Diels-Alder reactions

Bronsted acid-assisted chiral Lewis acid (BLA) was highly effective as a chiral catalyst for the enantioselective Diels-Alder reaction of both α- substituted and α-unsubstituted α,β-enals with various dienes. Hydroxy groups in optically active binaphthol derivatives and boron reagents with electron-withdrawing substituents were used as Bronsted acids and Lewis acids, respectively. Intramolecular Bronsted acids in a chiral BLA catalyst played an important role in accelerating the rate of Diels-Alder reactions and in producing a high level of enantioselectivity. In particular, excellent enantioselectivity was achieved due to intramolecular hydrogen bonding interaction and attractive π-π donor-acceptor interaction in the transition-state assembly by hydroxy aromatic groups in a chiral BLA catalyst.