42908-33-8

Basic information

• Product Name: 3-(TOLUENE-4-SULFONYLAMINO)-PROPIONIC ACID
• Synonyms: beta-alanine, N-[(4-methylphenyl)sulfonyl]-;N-[(4-methylphenyl)sulfonyl]-beta-alanine;3-[(4-methylphenyl)sulfonylamino]propanoic acid;3-[(4-methylphenyl)sulfonylamino]propionic acid;Propionic acid, 3-(4-tolylsulfonylamido)-;3-((4-methylphenyl)sulfonamido)propanoicacid
• CAS NO: 42908-33-8
• Molecular Formula: C₁₀H₁₃NO₄S
• Molecular Weight: 243.28
• Mol File: 42908-33-8.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 442.3°C at 760 mmHg
• Flash Point: 221.3°C
• Appearance: /
• Vapor Pressure: 1.34E-08mmHg at 25°C
• CAS DataBase Reference: 3-(TOLUENE-4-SULFONYLAMINO)-PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(TOLUENE-4-SULFONYLAMINO)-PROPIONIC ACID(42908-33-8)
• EPA Substance Registry System: 3-(TOLUENE-4-SULFONYLAMINO)-PROPIONIC ACID(42908-33-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 42908-33-8(Hazardous Substances Data)

Usage

Description

3-(TOLUENE-4-SULFONYLAMINO)-PROPIONIC ACID is a chemical compound with the molecular formula C11H13NO4S. It is a derivative of toluene and features a sulfonamide group attached to the toluene ring, which imparts unique characteristics and reactivity to the molecule. 3-(TOLUENE-4-SULFONYLAMINO)-PROPIONIC ACID is utilized as a building block in the synthesis of various pharmaceuticals and organic compounds, making it a valuable component in organic synthesis and medicinal chemistry.

Uses

Used in Pharmaceutical Synthesis:
3-(TOLUENE-4-SULFONYLAMINO)-PROPIONIC ACID is used as a building block for the development of pharmaceuticals due to its unique reactivity and the ability to form a variety of derivatives with potential medicinal properties.
Used in Organic Synthesis:
In the field of organic synthesis, 3-(TOLUENE-4-SULFONYLAMINO)-PROPIONIC ACID is used as a reagent to create a range of organic compounds, leveraging its sulfonamide group for diverse chemical reactions.
Used in Medicinal Chemistry:
3-(TOLUENE-4-SULFONYLAMINO)-PROPIONIC ACID is utilized in medicinal chemistry for the synthesis of bioactive compounds and potential drug candidates, taking advantage of its unique structural features to design novel therapeutic agents.
Used in Research and Development:
3-(TOLUENE-4-SULFONYLAMINO)-PROPIONIC ACID is also used in research and development settings to explore its properties and potential applications in creating new drugs and organic compounds, contributing to the advancement of chemical and medical sciences.

InChI:InChI=1/C10H13NO4S/c1-8-2-4-9(5-3-8)16(14,15)11-7-6-10(12)13/h2-5,11H,6-7H2,1H3,(H,12,13)/p-1

Upstream product

• 2619-16-1 N,N-bis[(2-cyanoethyl)]-4-methylbenzenesulfonamide 
• 107-94-8 chloropropionic acid 
• 70-55-3 toluene-4-sulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 107-95-9 3-amino propanoic acid 
• 718633-51-3 N-1-(3-oxopropyl)-4-methyl-1-benzenesulfonamide 
• 50487-71-3 4-methyl-N-(2-propenyl)benzenesulfonamide 
• 3634-89-7 N-(p-toluenesulfonyl)aziridine 
• 124-38-9 carbon dioxide 

Downstream Products

• 62456-75-1 N-[(4-methylphenyl)sulfonyl]-β-alanine methyl ester 
• 61341-03-5 N-(toluene-4-sulfonyl)-β-alanyl chloride 
• 68768-96-7 (3aS)-3c-[N-(toluene-4-sulfonyl)-β-alanyloxy]-2t-[N-(toluene-4-sulfonyl)-β-alanyloxymethyl]-(3ar,9ac)-2,3,3a,9a-tetrahydro-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-ylideneamine 
• 122081-15-6 3-{[(4-methylphenyl)sulfonyl]amino}-1-pyrrolidinylpropan-1-one 
• 90303-19-8 2-(N-Tos-β-Ala)aminopyrimidine 
• 78221-08-6 N-(2-Imino-thiazolo[4,5-b]quinoxalin-3-yl)-3-(toluene-4-sulfonylamino)-propionamide 
• 80613-80-5 N-(2-Oxo-2H-chromen-3-yl)-3-(toluene-4-sulfonylamino)-propionamide 
• 76616-47-2 N-[(4-methylphenyl)sulfonyl]-β-alanine ethyl ester 
• 84708-83-8 3,6-dinitro-9-(N-tosyl-β-alanyl)carbazole 
• 90303-30-3 N-(Pyridin-4-ylcarbamoylmethyl)-3-(toluene-4-sulfonylamino)-propionamide 
• 90303-32-5 N-[2-(Pyridin-4-ylcarbamoyl)-ethyl]-3-(toluene-4-sulfonylamino)-propionamide 
• 115946-47-9 1-[(4-methylphenyl)sulfonyl]azetidin-2-one 
• 84708-68-9 9-(N-tosyl-β-alanyl)carbazole 
• 78211-15-1 2-(N-Tos-β-Ala)hydrazino-4(H)-1,3,4-thiadiazino<5,6-b>quinoxaline 

Relevant articles and documents

Ni-Catalyzed Carboxylation of Aziridines en Route to β-Amino Acids

A Ni-catalyzed reductive carboxylation of N-substituted aziridines with CO2 at atmospheric pressure is disclosed. The protocol is characterized by its mild conditions, experimental ease, and exquisite chemo- and regioselectivity pattern, thus unlocking a new catalytic blueprint to access β-amino acids, important building blocks with considerable potential as peptidomimetics.

Fluorescent probe for detecting peroxynitrite ions, preparation method and applications thereof

The invention provides a fluorescent probe for detecting peroxynitrite ions. The fluorescent probe provided by the invention has high specificity, is not interfered by other components in a corresponding peroxynitrite ion detection process, can be used fo

Synthesis, Characterization, and Reactivity of an Ethynyl Benziodoxolone (EBX)-Acetonitrile Complex

The synthesis of a crystalline ethynyl-1,2-benziodoxol-3(1H)-one (EBX)-acetonitrile complex is described. EBX has been widely used as an active species for a variety of reactions; however, its high instability has so far prevented its isolation. The EBX-acetonitrile is self-assembled into a double-layered honeycomb structure through weak hypervalent iodine secondary interactions and hydrogen bonding. The N-ethynylation of a variety of sulfonamides using the EBX-acetonitrile complex as a substrate under mild conditions is also described.