42973-56-8 Usage
General Description
2-Hydroxy-3-methoxyphenylacetonitrile, also known as guaiacol acetonitrile, is a chemical compound with the molecular formula C9H9NO2. It is a nitrile derivative of guaiacol, a natural organic compound found in wood smoke. 2-Hydroxy-3-methoxyphenylacetonitrile has a variety of industrial applications, including in the production of drugs and pharmaceuticals. It is often used as a precursor for the synthesis of various organic compounds, and its nitrile functional group makes it a versatile building block in organic chemistry. This chemical has also been investigated for its potential use in the development of new drugs and pharmaceuticals due to its unique structure and properties.
Check Digit Verification of cas no
The CAS Registry Mumber 42973-56-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,9,7 and 3 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 42973-56:
(7*4)+(6*2)+(5*9)+(4*7)+(3*3)+(2*5)+(1*6)=138
138 % 10 = 8
So 42973-56-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H9NO2/c1-12-8-4-2-3-7(5-6-10)9(8)11/h2-4,11H,5H2,1H3
42973-56-8Relevant articles and documents
Mechanism of simmondsin decomposition during sodium hydroxide treatment
Van Boven,Laga,Leonard,Busson,Holser,Decuypere,Flo,Lievens,Cokelaere
, p. 1260 - 1264 (2003)
Jojoba seed meal shows appetite-suppressing activity due to the presence of simmondsin. This pharmacological activity disappears with treatment of the meal with sodium hydroxide. To elucidate this mechanism of inactivation, the reaction of simmondsin in 1 N NaOH at 20 °C was monitored as a function of time. The end products of the reaction as well as intermediates were isolated and identified. The half-life of simmondsin was ～60 min with D-glucose and 2-hydroxy-3-methoxyphenylacetonitrile as reaction end products. The reaction mechanism could be elucidated by the isolation of isosimmondsin and a simmondsin lactone derivative. Those compounds were isolated and purified by a combination of column chromatography and HPLC and identified mainly by HRMS and NMR spectroscopy.
