4304-40-9 Usage
Description
Thenium closylate is a chemical compound that has been found to possess anthelmintic properties, making it effective in treating infections caused by parasitic nematodes, particularly those that reside in the stomach and intestines.
Uses
Used in Veterinary Medicine:
Thenium closylate is used as an anthelmintic agent for the treatment of parasitic nematode infections in animals, particularly those affecting the stomach and intestines. Its effectiveness in eliminating these parasites helps to improve the overall health and well-being of the animals.
Used in Human Medicine:
Though not explicitly mentioned in the provided materials, thenium closylate may also have potential applications in human medicine for treating similar parasitic nematode infections, given its anthelmintic properties. However, further research and clinical trials would be necessary to confirm its safety and efficacy in humans.
Originator
Thenium closylate,ZYF Pharm Chemical
Manufacturing Process
2-Chlormethylthiophene (6.6 g) was added to a solution of 1-dimethylamino-
2-phenoxyethane (8.2 g) in acetone (45 ml). On standing for 30 min an oil
separeted. The resulting suspension was heated to reflux for a further 30 min
and cooled. On standing, the separated oil partially crystallized. The
supernatant liquors were decanted and the residue was recrystallized by
dissolution in warm isopropanol and careful precipitation with ethyl acetate or
ether to give colourless needles N,N-dimethyl-N-2-phenoxyethyl-N-2'-
thenylammonium chloride monohydrate, M.P. 85-86°C.A solution of free base of the last compound and p-chlorobenzenesulfonic acid
(molar ratio 1:1) were reacted together in boiling acetone. After 30 min the
solution was cooled and ethyl acetate added to precipitate a colourless solid of
N,N-dimethyl-N-(2-phenoxyethyl)-N-(2-thenyl)ammonium 4-
chlorbenzolsulfonate.
Therapeutic Function
Anthelmintic
Check Digit Verification of cas no
The CAS Registry Mumber 4304-40-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,0 and 4 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 4304-40:
(6*4)+(5*3)+(4*0)+(3*4)+(2*4)+(1*0)=59
59 % 10 = 9
So 4304-40-9 is a valid CAS Registry Number.
InChI:InChI=1/C15H20NOS.C6H5ClO3S/c1-16(2,13-15-9-6-12-18-15)10-11-17-14-7-4-3-5-8-14;7-5-1-3-6(4-2-5)10-11(8)9/h3-9,12H,10-11,13H2,1-2H3;1-4H,(H,8,9)/q+1;/p-1
