43076-33-1

Basic information

• Product Name: 1-Butanone, 1-(4-bromophenyl)-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-
• CAS NO: 43076-33-1
• Molecular Formula: C28H30BrNO2
• Molecular Weight: 492.456
• Mol File: 43076-33-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-Butanone, 1-(4-bromophenyl)-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butanone, 1-(4-bromophenyl)-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-(43076-33-1)
• EPA Substance Registry System: 1-Butanone, 1-(4-bromophenyl)-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-(43076-33-1)

Safety Data

• Hazardous Substances Data: 43076-33-1(Hazardous Substances Data)

Upstream product

• 115-46-8 C₁₈H₂₁NO 
• 168907-66-2 4'-bromo-4-iodobutyrophenone 
• 108-86-1 bromobenzene 
• 4559-96-0 1-(4-bromophenyl)-4-chlorobutan-1-one 

Downstream Products

• 43076-23-9 1-(4-bromophenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol 
• 154477-55-1 methyl 2-(4-(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)-2-methylpropanoate 

Relevant articles and documents

METHODS AND COMPOSITIONS FOR TREATING INFECTION

Provided herein are compositions and methods for treating or preventing infection.

Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2

The active site topology, substrate specificity, and biological roles of the human cytochrome P450 CYP2J2, which is mainly expressed in the cardiovascular system, are poorly known even though recent data suggest that it could be a novel biomarker and potential target for therapy of human cancer. This paper reports a first series of high-affinity, selective CYP2J2 inhibitors that are related to terfenadine, with Ki values as low as 160 nM, that should be useful tools to determine the biological roles of CYP2J2.