431-35-6 Usage
Description
3-Bromo-1,1,1-trifluoroacetone is a clear colorless to yellowish liquid that is a key intermediate in the synthesis of various organic compounds. It is known for its reactivity and is widely utilized in the preparation of different chemical entities.
Uses
Used in Pharmaceutical Industry:
3-Bromo-1,1,1-trifluoroacetone is used as a synthetic intermediate for the preparation of 3-nonylthio-1,1,1-trifluoropropan-2-one, which is an essential component in the development of pharmaceuticals. It is also used in the synthesis of cyclic tetrapeptides, which have potential applications in drug design and discovery.
Used in Chemical Synthesis:
In the field of chemical synthesis, 3-Bromo-1,1,1-trifluoroacetone is used as a reagent for the preparation of perfluoroalkylated trans-allylic alcohols. These compounds are valuable in the development of new materials and chemicals with unique properties.
Used in Material Science:
3-Bromo-1,1,1-trifluoroacetone is used as a building block in the synthesis of compounds containing trifluoromethyl and pentafluoroethyl ketone as zinc binding functional groups. These compounds have potential applications in material science, particularly in the development of new materials with enhanced properties.
General Description:
3-Bromo-1,1,1-trifluoroacetone is a versatile chemical intermediate that reacts with the potassium enolate of ethyl 4,4,4-trifluoroacetoacetate to yield ethyl 2,4-bis(trifluoromethyl)-4-hydroxydihydro-3-furoate, a compound with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 431-35-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,3 and 1 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 431-35:
(5*4)+(4*3)+(3*1)+(2*3)+(1*5)=46
46 % 10 = 6
So 431-35-6 is a valid CAS Registry Number.
InChI:InChI=1/C4H7F3O/c1-2-3(8)4(5,6)7/h3,8H,2H2,1H3
431-35-6Relevant articles and documents
Syntheses of Trifluoromethyl Heterocycles
Moazzam, Muhammad,Parrick, J.
, p. 1051 - 1053 (2007/10/02)
Mono and bicyclic heterocycles bearing trifluoromethyl substituent have been synthesized and characterized by spectral studies. 4(5)-Trifluoromethylimidazole (3) is prepared from the reaction of 3,3-dibromo-1,1,1-trifluoroacetone (2) with formaldehyde and ammonia.N-Methylation of 3 by phase transfer reaction gives 1-methyl-4-trifluoromethylimidazole (4). 2-Amino-4-trifluoromethylimidazole (5) is similarly obtained from 3-bromo-1,1,1-trifluoroacetone (1) and thiourea.The reaction of 1 with 2-aminopyridine and 2-aminothiazole gives 2-trifluoromethylimidazopyridine (7) and 6-trifluoromethylimidazothiazole (9) respectively.
