431043-99-1Relevant articles and documents
Antiangiogenic activity of synthetic dihydrobenzofuran lignans
Apers, Sandra,Paper, Dietrich,Buergermeister, Jutta,Baronikova, Slavka,van Dyck, Stefaan,Lemiere, Guy,Vlietinck, Arnold,Pieters, Luc
, p. 718 - 720 (2007/10/03)
A series of synthetic dihydrobenzofuran lignans, obtained by biomimetic oxidative dimerization of caffeic or ferulic acid methyl ester followed by derivatization reactions, was tested for its antiangiogenic activity in the CAM (chorioallantoic membrane) a
3',4-Di-O-methylcedrusin: synthesis, resolution and absolute configuration
Lemiere, Guy,Gao, Mei,Groot, Alex De,Dommisse, Roger,Lepoivre, Josef,et al.
, p. 1775 - 1780 (2007/10/02)
The title compound has been synthesised in racemic form by a biomimetic reaction sequence.The two enantiomers were resolved by column cromatography of one of the synthetic intermediates.On the basis of CD results a tentative absolute configuration for the synthetic enantiomers and natural 3',4-di-O-methylcedrusin is proposed.