43139-22-6

Basic information

• Product Name: GUANOSINE 5'-DIPHOSPHATE SODIUM SALT
• Synonyms: GUANOSINE 5'-DIPHOSPHATE SODIUM SALT;GUANOSINE-5'-DIPHOSPHATE MONOSODIUM SALT;GDP;5'-GDP 3NA;guanosine 5'-diphosphate sodium type I;GUANOSINE-5'-DIPHOSPHATE SODIUM SALT ULTRA PURE GRADE ;Guanosine-5''-diphosphoric acid monosodium salt;guanosine 5'-diphosphate sodium salt, Type I
• CAS NO: 43139-22-6
• Molecular Formula: C10H14N5NaO11P2
• Molecular Weight: 465.18
• Mol File: 43139-22-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: GUANOSINE 5'-DIPHOSPHATE SODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: GUANOSINE 5'-DIPHOSPHATE SODIUM SALT(43139-22-6)
• EPA Substance Registry System: GUANOSINE 5'-DIPHOSPHATE SODIUM SALT(43139-22-6)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 43139-22-6(Hazardous Substances Data)

Usage

Description

GUANOSINE 5'-DIPHOSPHATE SODIUM SALT, also known as Guanosine 5'-diphosphate sodium (GDP-Na), is a nucleotide that plays a crucial role in cellular signaling and protein synthesis. It is a derivative of guanosine, a nucleoside composed of guanine and ribose, and is involved in various biological processes, including signal transduction and energy transfer.

Uses

Used in GTP-γ-35S Functional Assays:
GUANOSINE 5'-DIPHOSPHATE SODIUM SALT is used as a substrate in GTP-γ-35S functional assays for studying the activity and regulation of G-protein coupled receptors (GPCRs). These assays help researchers understand the signaling pathways and interactions between GPCRs and their ligands, which are essential for various cellular functions.
Used in Y1 Agonist-Stimulated [35S]-Guanosine-5'-O-(3-Thio)triphosphate (GTPγS) Functional Binding:
In this application, GUANOSINE 5'-DIPHOSPHATE SODIUM SALT is used as a tool to investigate the binding properties and activation of Y1 receptors, a subtype of neuropeptide Y receptors. This helps researchers study the role of Y1 receptors in various physiological processes and their potential as therapeutic targets for conditions such as obesity, anxiety, and depression.
Used in the Expression and Purification of Recombinant Proteins:
GUANOSINE 5'-DIPHOSPHATE SODIUM SALT is utilized in the expression and purification of recombinant proteins, which are essential for various research and therapeutic applications. By using GDP-Na, researchers can study the structure, function, and interactions of these proteins, leading to a better understanding of their roles in cellular processes and the development of novel therapeutic strategies.