43191-23-7

Basic information

• Product Name: 2-Pyridinamine, 5-methyl-N-phenyl-
• CAS NO: 43191-23-7
• Molecular Formula: C12H12N2
• Molecular Weight: 184.241
• Mol File: 43191-23-7.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 2-Pyridinamine, 5-methyl-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinamine, 5-methyl-N-phenyl-(43191-23-7)
• EPA Substance Registry System: 2-Pyridinamine, 5-methyl-N-phenyl-(43191-23-7)

Safety Data

• Hazardous Substances Data: 43191-23-7(Hazardous Substances Data)

Upstream product

• 1003-73-2 3-picoline-N-oxide 
• 103-71-9 phenyl isocyanate 
• 59346-37-1 (3aS,7aS)-6-Methyl-3-phenyl-3a,7a-dihydro-3H-oxazolo[4,5-b]pyridin-2-one 
• 3510-66-5 2-Bromo-5-methylpyridine 
• 62-53-3 aniline 
• 1193779-39-3 diethyl [5-methyl-2-(phenylamino)pyridin-3-yl]phosphonate 
• 1603-41-4 (5-methyl-pyridin-2-yl)amine 
• 108-86-1 bromobenzene 
• 17282-00-7 3-bromo-5-methylpyridin-2-amine 
• 591-50-4 iodobenzene 
• 109-04-6 2-bromo-pyridine 
• 98-80-6 phenylboronic acid 

Downstream Products

• 99758-04-0 5-methyl-2-(N-phenylcarbamoylanilino)pyridine 
• 81416-34-4 5-methyl-1-phenylcarbamoyl-2-phenylimino-1,2-dihydropyridine 
• 88474-34-4 2-methylbenzo[4,5]imidazo[1,2-a]pyridine 
• 1383232-41-4 N-methyl-N-phenyl-2-amino-5-methylpyridine 
• 1570075-54-5 N-([1,1'-biphenyl]-2-yl)-5-methylpyridin-2-amine 

Relevant articles and documents

Rapid access to diverse α-carbolines through sequential transition metal catalyzed amination and direct C-H arylation

An efficient sequence of Pd catalyzed amination and direct C-H arylation for a synthesis of pharmacologically important α-carbolines is described. The outstanding feature in the synthetic sequence is that a combination of DBU and 2-(dicyclohexylphosphino)

PROSTACYCLIN RECEPTOR AGONIST

A compound represented by formula (I) or an isomer or a pharmaceutically acceptable salt thereof. The present invention also relates to an application of the same in preparing a drug for treating a disease related to a PGI2 receptor.

Ruthenium-catalyzed synthesis of indole derivatives from: N -aryl-2-aminopyridines and alpha-carbonyl sulfoxonium ylides

Indole is a ubiquitous structural motif with important applications in many areas of chemistry. Given this, a simple and efficient Ru(ii)-catalyzed synthesis of indole via intermolecular annulation of N-aryl-2-aminopyridines and sulfoxonium ylides was proposed and accomplished. Excellent selectivity and good functional group tolerance of this transformation were observed. This protocol provides easy access to a wide variety of useful indoles in the presence of a commercially available [Ru(p-cymene)Cl2]2 catalyst. A possible mechanism for the reaction pathway was also proposed. More importantly, this reaction will offer a useful method for the construction of enantioenriched indole frameworks.