432503-80-5

Basic information

• Product Name: (4-ethylpiperazin-1-yl)(3-methyl-4-nitrophenyl)methanone
• Synonyms: (4-ethylpiperazin-1-yl)(3-methyl-4-nitrophenyl)methanone
• CAS NO: 432503-80-5
• Molecular Weight: 277.323
• Mol File: 432503-80-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4-ethylpiperazin-1-yl)(3-methyl-4-nitrophenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-ethylpiperazin-1-yl)(3-methyl-4-nitrophenyl)methanone(432503-80-5)
• EPA Substance Registry System: (4-ethylpiperazin-1-yl)(3-methyl-4-nitrophenyl)methanone(432503-80-5)

Safety Data

• Hazardous Substances Data: 432503-80-5(Hazardous Substances Data)

Upstream product

• 5308-25-8 4-ethylpiperazine 
• 3113-71-1 3-methyl-4-nitrobenzoic acid 

Downstream Products

• 1234562-95-8 C₁₉H₂₆N₄O₃ 

Relevant articles and documents

Optimization of the phenylurea moiety in a phosphoinositide 3-kinase (PI3K) inhibitor to improve water solubility and the PK profile by introducing a solubilizing group and ortho substituents

Phosphoinositide 3-kinase (PI3K) is a promising anti-cancer target, because various mutations and amplifications are observed in human tumors isolated from cancer patients. Our dihydropyrrolopyrimidine derivative with a phenylurea moiety showed strong PI3