4333-70-4

Basic information

• Product Name: Benzene, 1-methyl-3-(1-phenylethenyl)-
• CAS NO: 4333-70-4
• Molecular Formula: C15H14
• Molecular Weight: 194.276
• Mol File: 4333-70-4.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methyl-3-(1-phenylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methyl-3-(1-phenylethenyl)-(4333-70-4)
• EPA Substance Registry System: Benzene, 1-methyl-3-(1-phenylethenyl)-(4333-70-4)

Safety Data

• Hazardous Substances Data: 4333-70-4(Hazardous Substances Data)

Upstream product

• 643-65-2 3-methyl benzophenone 
• 75-16-1 methylmagnesium bromide 
• 100-58-3 phenylmagnesium bromide 
• 585-74-0 3-Methylacetophenone 
• 98-86-2 acetophenone 
• 28987-79-3 m-tolylmagnesium bromide 
• 71-43-2 benzene 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 108-86-1 bromobenzene 
• 14428-98-9 N-benzyl-N-(1-phenylethylidene)amine 
• 90006-76-1 3-methyl-3-phenyl-diaziridine 
• 17933-03-8 m-tolylboronic acid 
• 63269-86-3 3-methyl-3-phenyl-3H-diazirine 
• 536-74-3 phenylacetylene 

Downstream Products

• 1355956-43-2 C₂₇H₂₆Si 
• 1355956-60-3 C₂₇H₂₄Si 
• 643-65-2 3-methyl benzophenone 
• 4073-49-8 3-phenyl-3-m-tolyl-propionic acid 
• 1443780-51-5 4-phenyl-4-(m-tolyl)butan-2-one 

Relevant articles and documents

Photoredox-Catalyzed α-Aminomethyl Carboxylation of Styrenes with Sodium Glycinates: Synthesis of γ-Amino Acids and γ-Lactams

A visible-light photoredox-catalyzed reductive α-aminomethyl carboxylation of styrenes with sodium glycinates and CO2 has been developed to synthesize a series of α,α-disubstituted γ-amino acids and γ-lactams with high efficiency and regioselectivity. Notably, CO2 released from the decarboxylation step can be reused for the subsequent carboxylation. Distinct from the previous reactions with the same type of substrates leading to simple decarboxylation and olefin hydroalkylation, this process involves additional CO2 sequestration, thus leading to olefin α-aminomethyl carboxylation. These findings not only provide new access to α,α-disubstituted γ-amino acids and γ-lactams but also serve as a proof of concept for CO2 reutilization in decarboxylation reactions.

Deaminative carbonylative coupling of alkylamines with styrenes under transition-metal-free conditions

A transition-metal-free deaminative carbonylation of alkylamines with styrenes has been developed. The reaction shows good functional group compatibility and various α,β-unsaturated ketones were obtained in moderate to good yields. The alkyl radical generated from Katritzky salts via base-promoted C-N bond cleavage is one of the key intermediates in this reaction. This journal is

Cu/Ni-Catalyzed Cyanomethylation of Alkenes with Acetonitrile for the Synthesis of β,γ-Unsaturated Nitriles

We have developed a protocol for the Cu/Ni-catalyzed cyanomethylation of alkenes with acetonitrile for the synthesis of β,γ-unsaturated nitriles. This is the first example of a direct coupling of the alkene sp2 C - H bond and the acetonitrile sp3 C - H bond for the preparation of β,γ-unsaturated nitriles. Acetonitrile, an inexpensive and stable solvent, is demonstrated to be a useful cyanomethyl source. The combination of copper and nickel catalysts resulted in a high reaction efficiency.