4338-95-8Relevant articles and documents
Synthesis of guanidinopropyl triethoxysilane and its homopolymer as a new class of organosilicon antibacterial agents
Cherkaev, G. V.,Drozdov, F. V.,Muzafarov, A. M.,Parshina, M. S.,Strukova, E. N.,Tarasenkov, A. N.
, (2020)
In current work guanidinopropyl triethoxysilane was synthesized for the first time. It was shown that this compound is stable as a salt of hydroiodic acid, however, it easily undergoes condensation when heated in water, forming a water-soluble branched homopolymer. Aqueous solutions of guanidinopropyl triethoxysilane and its branched homopolymer showed moderate antibacterial activity against Staphylococcus aureus and Escherichia coli.
Efficient Catalysts of Acyclic Guanidinium Iodide for the Synthesis of Cyclic Carbonates from Carbon Dioxide and Epoxides under Mild Conditions
Aoyagi, Naoto,Endo, Takeshi,Furusho, Yoshio
, p. 150 - 158 (2019/12/26)
We have studied the synthesis of five-membered cyclic carbonates through the cycloaddition of CO 2 to epoxides by using acyclic guanidinium salts. We have found that the cycloaddition reactions proceed smoothly at ordinary temperatures and pressures and result in good yields when acyclic guanidinium iodides are employed as catalysts. Both cation moiety and anion moiety of the guanidinium salts play important roles in their catalytic activity. It is essential to have active hydrogens on the cation moiety as well as an iodide ion as the anion moiety so as to achieve good catalytic activity. Guanidinium iodides with three or more active hydrogens give cyclic carbonates in high yields in polar solvents such as 1-methylpyrrolidin-2-one, whereas the guanidinium iodides with one or two active hydrogens show good catalytic activity in less polar solvents such as 2-methyltetrahydrofuran.
Rapid access to novel 2-alkylthiopyrimidine derivatives and attempt of their Tacrine analogs synthesis
Derabli, Chamseddine,Boulcina, Raouf,Kirsch, Gilbert,Debache, Abdelmadjid
supporting information, p. 395 - 403 (2019/01/21)
A variety of novel 2-alkylthiopyrimidines were synthesized through simple condensation of arylidenemalononitriles with different 2-alkylthiouronium halide derivatives catalyzed by anhydrous potassium carbonate (K2CO3). The reactions have been carried out under mild conditions in i-PrOH, and the products were obtained in moderate to good yields with a simple work-up method. Subsequently, some examples of these compounds have been converted into Tacrine analogs by applying the Friedl?nder reaction.
