435278-02-7

Basic information

• Product Name: 1-chloro-5-fluoroisoquinoline
• Synonyms: 1-chloro-5-fluoroisoquinoline
• CAS NO: 435278-02-7
• Molecular Formula: C9H5ClFN
• Molecular Weight: 181.5941032
• Mol File: 435278-02-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 295.6±20.0 °C(Predicted)
• Appearance: /
• Density: 1.366±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 1.09±0.43(Predicted)
• CAS DataBase Reference: 1-chloro-5-fluoroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-5-fluoroisoquinoline(435278-02-7)
• EPA Substance Registry System: 1-chloro-5-fluoroisoquinoline(435278-02-7)

Safety Data

• Hazardous Substances Data: 435278-02-7(Hazardous Substances Data)

Usage

Description

1-Chloro-5-fluoroisoquinoline is a fluoroquinolone antibiotic that is a derivative of isoquinoline, a heterocyclic compound with a nitrogen-containing ring structure. It is known for its broad-spectrum antibacterial activity and is used in the pharmaceutical industry for the synthesis of novel antibacterial agents.

Uses

Used in Pharmaceutical Industry:
1-Chloro-5-fluoroisoquinoline is used as a potent antibacterial agent for the development of new and effective antibiotics. Its ability to inhibit bacterial DNA gyrase and topoisomerase IV makes it a potential candidate for this application.
Used in Agricultural and Veterinary Medicine:
1-Chloro-5-fluoroisoquinoline is used as a veterinary antimicrobial agent in agricultural and veterinary medicine. Its significant antibacterial properties have garnered interest in these fields for potential applications.

Upstream product

• 410086-25-8 5-fluoroisoquinolin-1(2H)-one 

Downstream Products

• 1259223-98-7 5-fluoro-1,3-dichloroisoquinoline 

Relevant articles and documents

Preparation method of formaldehyde-substituted aza-condensed ring compound

The invention provides a preparation method of a formaldehyde-substituted aza-condensed ring compound, comprising the following steps: by using an aza-condensed ring lactam compound as a starting material, carrying out halogenation reaction, methylation reaction and methyl oxidation reaction to obtain the formaldehyde-substituted aza-condensed ring compound. According to the preparation method ofthe formaldehyde-substituted aza-condensed ring compound, the whole synthesis route is good in step repeatability, mild in operation condition and high in safety, and large-scale production and industrial popularization are facilitated; post-treatment energy consumption is low, a large amount of toxic wastewater is not generated, no pollution is caused to the environment, the production safety level and the production cost are reduced, application of green and environment-friendly industrial production is facilitated, and wide application prospects are achieved.

HEPATITIS C VIRUS INHIBITORS

Hepatitis C virus inhibitors are disclosed having the general formula:(I) wherein R1, R2, R3, R', B, Y and X are described in the description. Compositions comprising the compounds and methods for using the compounds toinhibit HCV are also disclosed.