4358-72-9

Basic information

• Product Name: 3-PENTYLMETHANESULPHONATE
• Synonyms: 3-PENTYLMETHANESULPHONATE
• CAS NO: 4358-72-9
• Molecular Formula: C₆H₁₄O₃S
• Molecular Weight: 166.24
• Mol File: 4358-72-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 253.7°C at 760 mmHg
• Flash Point: 107.3°C
• Appearance: /
• Density: 1.07g/cm³
• Vapor Pressure: 0.0287mmHg at 25°C
• Refractive Index: 1.432
• CAS DataBase Reference: 3-PENTYLMETHANESULPHONATE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PENTYLMETHANESULPHONATE(4358-72-9)
• EPA Substance Registry System: 3-PENTYLMETHANESULPHONATE(4358-72-9)

Safety Data

• Hazardous Substances Data: 4358-72-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H14O3S/c1-4-6(5-2)9-10(3,7)8/h6H,4-5H2,1-3H3

Upstream product

• 949908-55-8 pentan-3-yl 2,2,2-trichloroacetimidate 
• 75-75-2 methanesulfonic acid 
• 584-02-1 2-pentanol 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 24254-57-7 1-ethyl-propyl hydroperoxide 
• 617-80-1 2-ethyl-butyronitrile 
• 2719-52-0 2-phenylpentane 
• 1196-58-3 (1-ethylpropyl)benzene 
• 367252-51-5 2-(1-ethylpropoxy)-1,3-dimethoxybenzene 
• 488705-88-0 3-(2,4-dichlorophenyl)-8-ethyl-1-methyl-7-(3-pentyl)-3,7-dihydro-1H-purine-2,6-dione 
• 488705-89-1 4-[(2,4-dichlorophenyl)amino]-2-ethyl-N-methyl-1-(3-pentyl)-1H-imidazole-5-carboxamide 
• 196618-13-0 oseltamivir 
• 367252-53-7 1,5-dibromo-3-(1-ethylpropoxy)-2,4-dimethoxybenzene 
• 367252-61-7 (1R,3S,4S,5S,6R)-5-(1-ethylpropoxy)-4,6-dihydroxycyclohexane-1,3-dicarboxylic acid 1-ethyl ester 
• 367252-55-9 5-(1-ethylpropoxy)-4,6-dimethoxyisophthalic acid diethyl ester 
• 367252-57-1 all-cis-5-(1-ethylpropoxy)-4,6-dimethoxycyclohexane-1,3-dicarboxylic acid diethyl ester 
• 367252-59-3 all-cis-5-(1-ethylpropoxy)-4,6-dihydroxycyclohexane-1,3-dicarboxylic acid diethyl ester 
• 6137-03-7 3-ethyl-2-pentanone 

Relevant articles and documents

Enantioselective Synthesis of Oseltamivir Phosphate (Tamiflu) via the Iron-Catalyzed Stereoselective Olefin Diazidation

We herein report a gram-scale, enantioselective synthesis of Tamiflu, in which the key trans-diamino moiety has been efficiently installed via an iron-catalyzed stereoselective olefin diazidation. This significantly improved, iron-catalyzed method is uniquely effective for highly functionalized yet electronically deactivated substrates that have been previously problematic. Preliminary catalyst structure-reactivity-stereoselectivity relationship studies revealed that both the iron catalyst and the complex substrate cooperatively modulate the stereoselectivity for diazidation. Safety assessment using both differential scanning calorimetry (DSC) and the drop weight test (DWT) has also demonstrated the feasibility of carrying out this iron-catalyzed olefin diazidation for large-scale Tamiflu synthesis.

Stereo-specific synthesis of shimikic acid derivatives with improved efficiency

The invention provides a multistep synthesis for the preparation of 4,5-diamino shikimic acid derivatives of formula 1starting from an isophthalic acid derivative of formula 24,5-Diamino shikimic acid derivatives are potent inhibitors of viral neuraminidase.