4361-00-6

Basic information

• Product Name: 3-OXO-3H-BENZO[F]CHROMENE-2-CARBOXYLIC ACID
• Synonyms: IFLAB-BB F1018-1512;AKOS BBS-00004750;3-OXO-3H-BENZO[F]CHROMENE-2-CARBOXYLIC ACID;RARECHEM AB KA K018;5,6-Benzocoumarine-3-carboxylic acid;2-Oxo-5,6-[1,3]butadieno-2H-1-benzopyran-3-carboxylic acid;3-Oxo-3H-naphtho[2,1-b]pyran-2-carboxylic acid;5,6-Benzocoumarin-3-carboxylic acid
• CAS NO: 4361-00-6
• Molecular Formula: C₁₄H₈O₄
• Molecular Weight: 240.21
• Mol File: 4361-00-6.mol
• Article Data: 37

Chemical Properties

• Melting Point: 236-239°C
• Boiling Point: 486.2 °C at 760 mmHg
• Flash Point: 194 °C
• Appearance: /
• Density: 1.487 g/cm³
• Vapor Pressure: 2.88E-10mmHg at 25°C
• Refractive Index: 1.719
• PKA: 1.68±0.20(Predicted)
• CAS DataBase Reference: 3-OXO-3H-BENZO[F]CHROMENE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-OXO-3H-BENZO[F]CHROMENE-2-CARBOXYLIC ACID(4361-00-6)
• EPA Substance Registry System: 3-OXO-3H-BENZO[F]CHROMENE-2-CARBOXYLIC ACID(4361-00-6)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 4361-00-6(Hazardous Substances Data)

Usage

General Description

3-OXO-3H-BENZO[F]CHROMENE-2-CARBOXYLIC ACID is a chemical compound with a molecular formula of C17H10O4. It belongs to the class of benzo[f]chromene carboxylic acids and is characterized by a 3-oxo-3H-benzo[f]chromene moiety and a carboxylic acid functional group. 3-OXO-3H-BENZO[F]CHROMENE-2-CARBOXYLIC ACID has potential biological and pharmaceutical applications as it exhibits various pharmacological activities, including antioxidant, anti-inflammatory, and antimicrobial properties. It is also known to have potential therapeutic effects against certain diseases, making it a subject of interest for researchers in various fields. Additionally, this compound can be used as a building block in the synthesis of other organic compounds and is of interest for further studies in medicinal chemistry and drug development.

InChI:InChI=1/C14H8O4/c15-13(16)11-7-10-9-4-2-1-3-8(9)5-6-12(10)18-14(11)17/h1-7H,(H,15,16)

Upstream product

• 4431-57-6 3-oxo-3H-benzo[f]chromene-2-carboxylic acid amide 
• 141-82-2 malonic acid 
• 731-90-8 N-(2-hydroxy-1-naphthalidene)aniline 
• 734-88-3 ethyl 5,6-benzocoumarin-3-carboxylate 
• 860452-66-0 5-(2-hydroxy-[1]naphthylmethylene)-1,3-diphenyl-barbituric acid 
• 303772-50-1 5-(2-hydroxy-[1]naphthylmethylene)-1,3-diphenyl-2-thio-barbituric acid 
• 4352-88-9 3-oxo-3H-benzo[f]chromene-2-carbonitrile 
• 2033-24-1 cycl-isopropylidene malonate 
• 708-06-5 2-hydroxynaphthalene-1-carbaldehyde 
• 71942-38-6 3-oxo-3H-benzo[f]chromene-2-carbonyl chloride 
• 25816-60-8 3-oxo-3H-naphtho[2,1-b]pyran-2-carboxylic acid methyl ester 
• 135-19-3 β-naphthol 
• 55135-70-1 (Z)-1-((phenylamino)methylene)naphthalen-2-one 
• 148642-24-4 1-((pyrimidine-2-ylimino)methyl)naphthalene-2-ol 

Downstream Products

• 64468-31-1 N-(4-Methylphenyl)-3-oxo-3H-naphtho<2,1-b>pyran-2-carboxamid 
• 64468-29-7 2-(N-Phenylcarboxamido)-3(H)-oxonaphtho<2,1-b>pyran 
• 35078-19-4 3-(2-Benzimidazolyl)-5,6-benzocumarin 
• 25816-60-8 3-oxo-3H-naphtho[2,1-b]pyran-2-carboxylic acid methyl ester 
• 734-88-3 ethyl 5,6-benzocoumarin-3-carboxylate 
• 64678-90-6 N-(4-Methoxyphenyl)-3-oxo-3H-naphtho<2,1-b>pyran-2-carboxamid 

Relevant articles and documents

Ionic liquid-mediated synthesis of coumarin-3-carboxylic acids via knoevenagel condensation of Meldrum's acid with ortho-hydroxyaryl aldehydes

A simple, efficient, and green protocol for synthesis of coumarin-3-carboxylic acids is described via Knoevenagel condensation of Meldrum's acid with ortho-hydroxyaryl aldehydes in [Hmim]Tfa ionic liquid, which was found to give better results than other ionic liquids. Furthermore, ionic liquid is easily reused without any appreciable loss in activity. Copyright Taylor & Francis Group, LLC.

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A two-photon benzocoumarin-NBD dyad for highly selective and sensitive ratiometric detection of H2S in biological samples

Hydrogen sulfide (H2S), the third endogenous gas signaling transmitter, plays an important role in the basic signal conduction process of human physiology and pathology. It is critical to monitor the dynamic change of H2S in living organisms. In this article, a two-photon ratiometric fluorescent probe (BCD) based on the benzocoumarin-NBD framework was first designed and synthesized. The probe showed large emission separation (about 115 nm), excellent selectivity, and high sensitivity. Moreover, it could be applied to ratiometric image endogenous H2S biosynthesis in the living cells and zebrafish.

Synthesis and Luminescent Properties of Eu3+ and Tb3+ Complexes with Coumarin-3-carboxylic Acids

Abstract: New Eu3+ and Tb3+ complex compounds [Ln(H2O)2L2]Cl?H2O were synthesized on the basis of coumarin-3-carboxylic acid and its derivatives. Composition and structure of the ligands an

Fluorescent probe, preparation method thereof, fluorescent probe test paper, and application of fluorescent probe test paper

The invention belongs to the technical field of biological mercaptan detection, and particularly relates to a fluorescent probe, a preparation method thereof, a fluorescent probe test paper, and an application of the fluorescent probe test paper. The fluorescent probe can specifically recognize biological mercaptan (Cys, Hcy and GSH), and has the advantages of easiness in preparation, low price, strong specificity, high sensitivity, and suitableness for the physiological pH; and the fluorescent probe test paper prepared by using the fluorescent probe can be used to quantitatively detect biological mercaptan in a urine sample through naked eyes, and has great application values in the fields of biomedicines and the like.