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437-99-0

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437-99-0 Usage

Description

(6alpha,11beta)-21-fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione is a synthetic corticosteroid belonging to the glucocorticoid class. It is characterized by its potent anti-inflammatory and immunosuppressive properties, which are utilized in the treatment of a range of conditions including asthma, allergies, and autoimmune disorders. (6alpha,11beta)-21-fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione operates by inhibiting the release of inflammatory mediators and suppressing the activity of immune cells, while also playing a role in the regulation of carbohydrate, protein, and fat metabolism. The 21-fluoro group in its molecular structure significantly enhances its potency and duration of action, making it a valuable component in pharmaceutical formulations.

Uses

Used in Pharmaceutical Industry:
(6alpha,11beta)-21-fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione is used as an anti-inflammatory and immunosuppressive agent for the treatment of various conditions such as asthma, allergies, and autoimmune disorders. Its application is based on its ability to inhibit the release of inflammatory mediators and suppress the activity of immune cells, providing relief from inflammation and immune system overactivity.
Used in Treatment of Metabolic Disorders:
In addition to its anti-inflammatory and immunosuppressive functions, (6alpha,11beta)-21-fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione is also used in the regulation of carbohydrate, protein, and fat metabolism. This makes it a potential therapeutic agent for conditions involving metabolic dysregulation, where its role in metabolic regulation can be beneficial.
Used in Enhancing Pharmaceutical Preparations:
The presence of the 21-fluoro group in the molecule of (6alpha,11beta)-21-fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione enhances its potency and duration of action. This characteristic makes it an important component in the development of more effective pharmaceutical preparations, particularly for conditions that require long-lasting anti-inflammatory and immunosuppressive effects.

Check Digit Verification of cas no

The CAS Registry Mumber 437-99-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,3 and 7 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 437-99:
(5*4)+(4*3)+(3*7)+(2*9)+(1*9)=80
80 % 10 = 0
So 437-99-0 is a valid CAS Registry Number.

437-99-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Pregna-1,4-diene-3,20-dione, 21-fluoro-11.β.,17-dihydroxy-6.α.-methyl-

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:437-99-0 SDS

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