4370-62-1 Usage
Description
Coenzyme Q4 (CoQ4) is a 4 isoprenyl group member of a family of ubiquinones that share a quinine chemical group but differ in the number of isoprenyl chemical subunits in their tail. It is a lipid-soluble component of cell membranes where it performs multiple functions such as electron and proton transport. CoQ4 is frequently used in comparison studies on the effect of isoprenyl chain length on CoQ functions or distribution.
Uses
Used in Pharmaceutical Industry:
Coenzyme Q4 is used as a research compound for studying the effect of isoprenyl chain length on CoQ functions or distribution. It helps in understanding the role of CoQ compounds in various biological processes and their potential applications in drug development.
Used in Scientific Research:
Coenzyme Q4 is used as a comparative tool in research studies to investigate the impact of isoprenyl chain length on the functions and distribution of CoQ compounds. This aids in advancing the understanding of the role of CoQ in cellular processes and its potential therapeutic applications.
Biochem/physiol Actions
Increases the fluorescence polarization of perylene incorporated into ubiquinone-depleted mitochondrial and bilayer vesicles prepared from mitochondrial phospholipids
Purification Methods
It is a redoil which can be purified by chromatography on SiO2 plates and eluted with Et2O/hexane. The purity is checked by HPLC (silica column using 7% Et2O/hexane). It has max 270 nm ( 14,800) in pet ether. [NMR and MS: Naruta J Org Chem 45 4097 1980, cf Morton Biochemical Spectroscopy (Adam Hilger, London, 1975) p 491]. It has also been dissolved in MeOH/EtOH (1:1 v/v) and kept at 5o until crystals appear [Lester & Crane Biochim Biophys Acta 32 497 1958].
Check Digit Verification of cas no
The CAS Registry Mumber 4370-62-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,7 and 0 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4370-62:
(6*4)+(5*3)+(4*7)+(3*0)+(2*6)+(1*2)=81
81 % 10 = 1
So 4370-62-1 is a valid CAS Registry Number.
InChI:InChI=1/C29H44O4/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-17-23(5)18-19-25-24(6)26(30)28(32-7)29(33-8)27(25)31/h12,14,16,18,28-29H,9-11,13,15,17,19H2,1-8H3/b21-14+,22-16+,23-18+
4370-62-1Relevant articles and documents
Controlling regiochemistry in negishi carboaluminations. Fine tuning the ligand on zirconium
Lipshutz, Bruce H.,Butler, Tom,Lower, Asher
, p. 15396 - 15398 (2007/10/03)
The species on the zirconocene catalyst is changed from two Cp's to the Brintzinger ligand and catalytic amounts of MAO are used to usually effect a >99% regiocontrol of Negishi carboaluminations of 1-alkynes in toluene. Copyright
Regio- and stereoselective synthesis of coenzymes Q(n) (n=2-10), vitamin K, and related polyprenylquinones
Naruta
, p. 4097 - 4104 (2007/10/02)
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