4374-35-0

Basic information

• Product Name: 1-Propanone, 2-bromo-1-(3-bromo-4-methoxyphenyl)-
• CAS NO: 4374-35-0
• Molecular Formula: C10H10Br2O2
• Molecular Weight: 321.996
• Mol File: 4374-35-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 2-bromo-1-(3-bromo-4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 2-bromo-1-(3-bromo-4-methoxyphenyl)-(4374-35-0)
• EPA Substance Registry System: 1-Propanone, 2-bromo-1-(3-bromo-4-methoxyphenyl)-(4374-35-0)

Safety Data

• Hazardous Substances Data: 4374-35-0(Hazardous Substances Data)

Usage

Type of compound

Organic compound, brominated derivative of a propanone with a substituted benzene ring

Usage

Key intermediate or building block in organic synthesis and pharmaceutical research, potential applications in pharmaceuticals, agrochemicals, and material science

Versatility

Chemical structure allows for the creation of diverse molecular entities with specific properties and functions.

Upstream product

• 1201-60-1 1-(1,2-dibromopropyl)-4-methoxybenzene 
• 64-19-7 acetic acid 
• 80167-12-0 2-bromo-4-(1,2-dibromo-propyl)-anisole 
• 121-97-1 4-Methoxypropiophenone 
• 104-45-0 4-n-propylanisole 
• 104-46-1 anethole 

Downstream Products

• 99-58-1 3-bromo-4-methoxybenzoic acid 
• 4374-36-1 1-(3-bromo-4-methoxyphenyl)-1-propanone 
• 98947-18-3 2,2-dibromo-1-(3-bromo-4-methoxy-phenyl)-propan-1-one 

Relevant articles and documents

Reactivity of substrates with multiple competitive reactive sites toward NBS under neat reaction conditions promoted by visible light

Regioselectivity of visible-light-induced transformations of a range of (hetero)aryl alkyl-substituted ketones bearing several competitive reactive sites (α-carbonyl, benzyl and aromatic ring) with N-bromosuccinimide (NBS) was studied under solvent-free reaction conditions (SFRC) and in the absence of inert-gas atmosphere, radical initiators and catalysts. An 8-W energy-saving household lamp was used for irradiation. Heterogeneous reaction conditions were dealt with throughout the study. All substrates were mono- or dibrominated at the α-carbonyl position, and additionally, some benzylic or aromatic bromination was observed in substrates with benzylic carbon atoms or electron-donating methoxy groups, respectively. Surprisingly, ipso-substitution of the acyl group with a bromine atom took place with (4-methoxynaphthyl) alkyl ketones. While the addition of the radical scavenger TEMPO (2,2,6,6-tetramethylpiperidin-1-yloxy) decreased the extent of α- and ring bromination, it completely suppressed the benzylic bromination and α,α-dibromination with NBS under SFRC.