437999-04-7

Basic information

• Product Name: 1(2H)-Pyridinebutanimidamide, 3,6-dihydro-4-phenyl-
• CAS NO: 437999-04-7
• Molecular Formula: C15H21N3
• Molecular Weight: 243.352
• Mol File: 437999-04-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1(2H)-Pyridinebutanimidamide, 3,6-dihydro-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(2H)-Pyridinebutanimidamide, 3,6-dihydro-4-phenyl-(437999-04-7)
• EPA Substance Registry System: 1(2H)-Pyridinebutanimidamide, 3,6-dihydro-4-phenyl-(437999-04-7)

Safety Data

• Hazardous Substances Data: 437999-04-7(Hazardous Substances Data)

Upstream product

• 43064-12-6 1,2,3,6-tetrahydro-4-phenylpyridine hydrochloride 
• 62099-25-6 4-(4-phenyl-3,6-dihydro-1(2H)-piridinyl)butanenitrile 

Downstream Products

• 437995-34-1 8-nitro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone 

Relevant articles and documents

4-Phenyl-1,2,3,6-tetrahydropyridine, an excellent fragment to improve the potency of PARP-1 inhibitors

We have shown that a 4-phenyl-1,2,3,6-tetrahydropyridine fragment plays an important role in improving inhibitory potency against poly(ADP-ribose) polymerase-1 (PARP-1). Various benzamide analogues linked with this fragment via alkyl spacers have been prepared and evaluated. As a result, some of them have been found to be highly potent PARP-1 inhibitors.