438221-62-6

Basic information

• Product Name: 3-(3-CHLORO-4-FLUORO-PHENOXYMETHYL)-4-METHOXY-BENZALDEHYDE
• Synonyms: AKOS B000997;3-(3-CHLORO-4-FLUORO-PHENOXYMETHYL)-4-METHOXY-BENZALDEHYDE;ART-CHEM-BB B000997;AK-968/41170459;ARONIS015576;Oprea1_812874;STK301796;ZINC00373469
• CAS NO: 438221-62-6
• Molecular Formula: C15H12ClFO3
• Molecular Weight: 294.71
• Mol File: 438221-62-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 436.4±45.0 °C(Predicted)
• Appearance: /
• Density: 1.304±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 3-(3-CHLORO-4-FLUORO-PHENOXYMETHYL)-4-METHOXY-BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-CHLORO-4-FLUORO-PHENOXYMETHYL)-4-METHOXY-BENZALDEHYDE(438221-62-6)
• EPA Substance Registry System: 3-(3-CHLORO-4-FLUORO-PHENOXYMETHYL)-4-METHOXY-BENZALDEHYDE(438221-62-6)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 438221-62-6(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 52577-09-0 3-(chloromethyl)-4-methoxybenzaldehyde 
• 2613-23-2 3-chloro-4-fluorophenol 

Relevant articles and documents

Alkylation of NH-, OH-, and SH-acids in the presence of potassium carbonate: 1. Functionalization of chloromethyl group of alkoxy-substituted aromatic aldehydes

An easily scalable, economocal, and more safe method for the preparation of 3-chloromethyl-4-methoxybenzaldehyde was developed. The latter was subjected to reactions with NH-, OH-, and SH-acids in the presence of potassium carbonate to obtain new aromatic aldehydes in high yields.