4383-25-9

Basic information

• Product Name: N-BENZYLCYCLOHEXYLAMINE
• Synonyms: Benzyl(cyclohexyl)amine;Benzylcyclohexylamine;Cyclohexylbenzylamine;N-Cyclohexylbenzylamine;N-(phenylmethyl)cyclohexanamine
• CAS NO: 4383-25-9
• Molecular Formula: C₁₃H₁₉N
• Molecular Weight: 189.2967
• Mol File: 4383-25-9.mol
• Article Data: 197

Chemical Properties

• Melting Point: 149 °C
• Boiling Point: 289.8 °C at 760 mmHg
• Flash Point: 130.6 °C
• Appearance: /
• Density: 0.97 g/cm³
• Vapor Pressure: 0.00215mmHg at 25°C
• Refractive Index: 1.536
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 10.05±0.20(Predicted)
• CAS DataBase Reference: N-BENZYLCYCLOHEXYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-BENZYLCYCLOHEXYLAMINE(4383-25-9)
• EPA Substance Registry System: N-BENZYLCYCLOHEXYLAMINE(4383-25-9)

Safety Data

• Hazardous Substances Data: 4383-25-9(Hazardous Substances Data)

Usage

General Description

N-BENZYLCYCLOHEXYLAMINE is a chemical compound that belongs to the class of secondary amines and contains a benzyl group and a cyclohexyl group. It is used in the synthesis of pharmaceuticals and acts as a ligand in catalysis reactions. N-BENZYLCYCLOHEXYLAMINE has a wide range of applications, including in the production of organic solvents, corrosion inhibitors, and in the development of new materials. It is considered to be a versatile building block for the synthesis of various organic compounds and plays a crucial role in the field of organic chemistry. Additionally, it is important to handle N-BENZYLCYCLOHEXYLAMINE with care, as it may be hazardous and requires proper safety precautions in its handling and use.

InChI:InChI=1/C13H19N/c1-3-7-12(8-4-1)11-14-13-9-5-2-6-10-13/h1,3-4,7-8,13-14H,2,5-6,9-11H2

Upstream product

• 1759-68-8 N-benzoylcyclohexylamine 
• 53181-35-4 benzyl-cyclohexyl-nitroso-amine 
• 64-18-6 formic acid 
• 108-94-1 cyclohexanone 
• 100-46-9 benzylamine 
• 2211-66-7 N-phenyl(methylidene)cyclohexanamine 
• 108-91-8 cyclohexylamine 
• 100-51-6 benzyl alcohol 
• 908094-04-2 phenyldiazomethane 
• 5577-68-4 cyclohexylamino-trimethyl-silane 
• 100-39-0 benzyl bromide 
• 100-52-7 benzaldehyde 
• 56249-48-0 1-(benzylamino)cyclohexane-1-carbonitrile 
• 27845-53-0 (E)-N-cyclohexyl-1-phenylmethanimine 

Downstream Products

• 92744-64-4 benzyl-cyclohexyl-dithiocarbamic acid 
• 102309-79-5 benzyl-cyclohexyl-(2-piperidino-ethyl)-amine 
• 78822-59-0 N-benzyl-N-cyclohexylbenzenesulfinamide 
• 69601-16-7 N-Benzyl-N-cyclohexyl-4-(2-oxo-1,2-dihydro-quinolin-6-yloxy)-butyramide 
• 111267-96-0 N-cyclohexyl-N-<(trimethylsilyl)methyl>benzylamine 
• 27845-53-0 (E)-N-cyclohexyl-1-phenylmethanimine 
• 2211-66-7 N-phenyl(methylidene)cyclohexanamine 
• 108-91-8 cyclohexylamine 
• 190271-48-8 1(R)-Amino-2(R)-phenyl-3(R)-t-butyldimethylsilyloxymethylcyclohexane 
• 108-88-3 toluene 
• 1367728-79-7 N-benzyl-N-cyclohexylaminomethane-P-(hydroxymethyl)phosphinic acid 
• 1367728-69-5 N-cyclohexylaminomethane-P-(hydroxymethyl)phosphinic acid 
• 1421364-78-4 C₂₈H₃₅N 
• 1431660-32-0 C₁₅H₁₈Cl₃NO 

Relevant articles and documents

T-shaped (D)2–A–π–A type sensitizers incorporating indoloquinoxaline and triphenylamine for organic dye-sensitized solar cells

Four novel T-shaped metal-free organic sensitizers QX22–25 based on triphenylamine and indoloquinoxaline have been successfully designed and synthesized as a (D)2–A–π–A type structure. These dye sensitizers have two triphenylamine donors attach

Silver/manganese dioxide nanorod catalyzed hydrogen-borrowing reactions and tert-butyl ester synthesis

Silver/manganese dioxide (Ag@MnO2) nanorods are synthesized and characterized by scanning electron microscopy, transmission electron microscopy, energy dispersive X-ray spectroscopy, X-ray powder diffraction, and X-ray photoelectron spectroscopy. It was discovered that Ag@MnO2 nanorods can realize hydrogen-borrowing reactions in high yields and are also effective for the synthesis of tert-butyl esters from aryl cyanides and tert-butyl hydroperoxide in a short period of time. Mechanistic experiments revealed that this catalytic system acts as a Lewis acid in hydrogen-borrowing reactions, while the synthesis of tert-butyl esters occurs through a radical pathway. This is the first report on the excellent catalytic activity of Ag@MnO2 nanorods as a catalyst.

BF3·Et2O as a metal-free catalyst for direct reductive amination of aldehydes with amines using formic acid as a reductant

A versatile metal- and base-free direct reductive amination of aldehydes with amines using formic acid as a reductant under the catalysis of inexpensive BF3·Et2O has been developed. A wide range of primary and secondary amines and diversely substituted aldehydes are compatible with this transformation, allowing facile access to various secondary and tertiary amines in high yields with wide functional group tolerance. Moreover, the method is convenient for the late-stage functionalization of bioactive compounds and preparation of commercialized drug molecules and biologically relevant N-heterocycles. The procedure has the advantages of simple operation and workup and easy scale-up, and does not require dry conditions, an inert atmosphere or a water scavenger. Mechanistic studies reveal the involvement of imine activation by BF3and hydride transfer from formic acid.