438470-79-2Relevant articles and documents
Organocatalyst Efficiency in the α-Aminoxylation and α-Hydrazination of Carbonyl Derivatives in Aqueous Media or in a Ball-Mill
Veverková, Eva,Modrocká, Viktória,?ebesta, Radovan
, p. 1191 - 1195 (2017/03/11)
Pyrrolidine-derived organocatalysts have been tested in two types of α-heterofunctionalization reactions in aqueous media or under solvent-free ball-milling conditions. The best results in terms of both activity and enantioselectivity were obtained with O
Heterogeneous Dipeptide-Catalyzed α-Amination of Aldehydes in a Continuous-Flow Reactor: Effect of Residence Time on Enantioselectivity
?tv?s, Sndor B.,Szloszr, Aliz,Mndity, Istvn M.,Fül?p, Ferenc
supporting information, p. 3671 - 3680 (2016/01/25)
A solid-supported dipeptide-catalyzed continuous-flow process was developed for the direct enantioselective α-amination of aldehydes with dibenzyl azodicarboxylate as the electrophilic nitrogen source. With residence time control as an efficient tool for
Remarkable reaction rate and excellent enantioselective direct α-amination of aldehydes with azodicarboxylates catalyzed by pyrrolidinylcamphor-derived organocatalysts
Liu, Pang-Min,Chang, Chihliang,Reddy, Raju Jannapu,Ting, Ying-Fang,Kuan, Hsuan-Hao,Chen, Kwunmin
supporting information; experimental part, p. 42 - 46 (2010/03/24)
Remarkable reaction rate and excellent enantioselective direct α-amination of unmodified aldehydes with various azodicarboxylates was catalyzed by pyrrolidinylcamphor organocatalyst 2a (5 mol-%) to provide the desired aminated products with excellent chemical yields and high to excellent levels of enantioselectivity (up to >99%ee) at 0 °C in CH 2Cl2.