4389-22-4

Basic information

• Product Name: 1,3-Benzodioxol-2-one, hexahydro-
• CAS NO: 4389-22-4
• Molecular Formula: C7H10O3
• Molecular Weight: 142.155
• Mol File: 4389-22-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1,3-Benzodioxol-2-one, hexahydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Benzodioxol-2-one, hexahydro-(4389-22-4)
• EPA Substance Registry System: 1,3-Benzodioxol-2-one, hexahydro-(4389-22-4)

Safety Data

• Hazardous Substances Data: 4389-22-4(Hazardous Substances Data)

Usage

General Description

1,3-Benzodioxol-2-one, hexahydro- is a chemical compound with the molecular formula C6H8O3. It is commonly known as tetrahydro-1,3-benzodioxol-2-one and is a colorless liquid with a mild, sweet odor. This chemical is used as a solvent and in the production of plastics, resins, and pharmaceuticals. It is also used as a precursor in the synthesis of other organic compounds. However, it is important to handle this chemical with caution as it can be toxic if ingested or inhaled, and it may cause skin irritation upon contact. Proper safety measures and handling procedures should be followed when working with 1,3-Benzodioxol-2-one, hexahydro-.

Upstream product

• 56155-84-1 cis-Hexahydrobenzo<1,3>dioxol-2-thion 
• 74-88-4 methyl iodide 
• 1792-81-0 cis-1,2-cyclohexane 
• 79-37-8 oxalyl dichloride 
• 1460-57-7 trans-1,2-cyclohexandiol 
• 108-24-7 acetic anhydride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 16166-55-5 trans-4,5-hexahydrobenzo-1,3-dioxolane-2-thione 
• 57-13-6 urea 
• 109-65-9 1-bromo-butane 
• 124-38-9 carbon dioxide 
• 286-20-4 cyclohexene oxide 

Downstream Products

• 1792-81-0 cis-1,2-cyclohexane 

Relevant articles and documents

Convenient synthesis of ethylene carbonates from carbon dioxide and 1,2-diols at atmospheric pressure of carbon dioxide

An efficient and convenient synthesis of ethylene carbonates was achieved by the reaction of carbon dioxide with 1,2-diols in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU), followed by treatment with 1-bromobutane. This DBU-promoted transformation proceeded at an atmospheric pressure of carbon dioxide at 25 °C and gave ethylene carbonates in good yields.

Lipophilic oligopeptides for chemo- and enantioselective acyl transfer reactions onto alcohols

Inspired by the extraordinary selectivities of acylases, we envisioned the use of lipophilic oligopeptidic organocatalysts for the acylative kinetic resolution/desymmetrization of rac- and meso-cycloalkane-1,2-diols. Here we describe in a full account the discovery and development process from the theoretical concept to the final catalyst, including scope and limitations. Competition experiments with various alcohols and electrophiles show the full potential of the employed oligopeptides. Additionally, we utilized NMR and IR-spectroscopic methods as well as computations to shed light on the factors responsible for the selectivity. The catalyst system can be readily modified to a multicatalyst by adding other catalytically active amino acids to the peptide backbone, enabling the stereoselective one-pot synthesis of complex molecules from simple starting materials.

Reaction of various oxiranes and carbon dioxide. Synthesis and aminolysis of five-membered cyclic carbonates

Various oxiranes reacted with carbon dioxide at 100 °C using lithium bromide as a catalyst under atmospheric pressure to afford the corresponding five-membered cyclic carbonates quantitatively. The rate of the reaction increased as the bulkiness of substituents on the oxirane ring was reduced or an electron-withdrawing group was introduced on the oxirane ring. The stereochemistry of the reaction of oxirane and carbon dioxide was retention without loss of optical purity. When substituted phenylethylene carbonates were reacted with benzylamine, the selectivity to afford secondary alcohol increased as the electron-withdrawing ability of the para-substituent increased.