439271-80-4

Basic information

• Product Name: Formamide, N-[(1R)-1-phenylpropyl]-
• CAS NO: 439271-80-4
• Molecular Formula: C10H13NO
• Molecular Weight: 163.219
• Mol File: 439271-80-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Formamide, N-[(1R)-1-phenylpropyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Formamide, N-[(1R)-1-phenylpropyl]-(439271-80-4)
• EPA Substance Registry System: Formamide, N-[(1R)-1-phenylpropyl]-(439271-80-4)

Safety Data

• Hazardous Substances Data: 439271-80-4(Hazardous Substances Data)

Upstream product

• 37643-54-2 N-[(4-methylbenzene-1-sulfonyl)(phenyl)methyl]formamide 
• 557-20-0 diethylzinc 

Downstream Products

• 1364683-93-1 (R)-N-(4-((3-(1-(4-(tert-butyl)phenyl)propyl)thioureido)methyl)-2-fluorophenyl)methanesulfonamide 
• 1364683-77-1 (R)-N-(4-((3-(1-(4-(tert-butyl)phenyl)propyl)thioureido)methyl)phenyl)methanesulfonamide 
• 1213091-61-2 (R)-1-(4-(tert-butyl)phenyl)propan-1-amine 
• 694529-70-9 1-[1-(4-amino-phenyl)-propyl]-3-(4-tert-butyl-benzyl)-thiourea 
• 694529-66-3 N-[1-(4-amino-phenyl)-propyl]-formamide 
• 694529-68-5 4-((R)-1-Amino-propyl)-phenylamine 
• 694529-64-1 N-[1-(4-nitro-phenyl)-propyl]-formamide 
• 2941-20-0 1-phenylpropylamine 

Relevant articles and documents

Development of chiral catalysts by asymmetric activation for highly enantioselective diethylzinc addition to imines

Based on the asymmetric activation concept, a library of chiral zinc complexes in situ formed by the combination of diimines derived from chiral 1,2-diphenyl-ethanene-1,2-diamine, BINOL derivatives, and diethylzinc are evaluated in the asymmetric addition of diethylzinc to N-acylimines. In the presence of 10 mol% L3ZnA1, high enantioselectivities and yields were provided for a wide range of aromatic imines in 1,2-dichloroethane at -25 °C.

Discovery of chiral catalysts by asymmetric activation for highly enantioselective diethylzinc addition to imines: Using racemic and achiral diimines as effective activators

A library of chiral zinc complexes formed in situ by the combination of achiral and racemic diimines with 3,3′-di(3,5-ditrifluoromethylphenyl)- BINOL and diethylzinc were evaluated in the asymmetric addition of diethylzinc to N-acylimines. In the presence of 10 mol % of chiral ligand 4 and racemic diimine 5, high enantioselectivities of up to 97% ee and yields of up to 96% were achieved for a wide range of aromatic imines in dichloromethane at -30°C.