439916-75-3

Basic information

• Product Name: Carbamic acid, [2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)amino]-2-oxoethyl]-, phenylmethyl ester
• CAS NO: 439916-75-3
• Molecular Formula: C18H15N3O5
• Molecular Weight: 353.334
• Mol File: 439916-75-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)amino]-2-oxoethyl]-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)amino]-2-oxoethyl]-, phenylmethyl ester(439916-75-3)
• EPA Substance Registry System: Carbamic acid, [2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)amino]-2-oxoethyl]-, phenylmethyl ester(439916-75-3)

Safety Data

• Hazardous Substances Data: 439916-75-3(Hazardous Substances Data)

Upstream product

• 85-44-9 phthalic anhydride 
• 5680-83-1 N-(benzyloxycarbonyl)glycine hydrazide 

Downstream Products

• 439916-79-7 [(2-Benzyloxycarbonylamino-acetyl)-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-amino]-acetic acid methyl ester 
• 439916-81-1 (R)-2-[(2-Benzyloxycarbonylamino-acetyl)-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-amino]-propionic acid methyl ester 
• 439916-83-3 (R)-2-[(2-Benzyloxycarbonylamino-acetyl)-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-amino]-3-methyl-butyric acid benzyl ester 
• 662148-81-4 N'-(benzyloxycarbonyl)-N^α-methyl-N^β-(phthaloyl)glycinehydrazide 
• 662148-72-3 N^α-benzyl-N'-(benzyloxycarbonyl)-N^β,N^β-bis(tert-butyloxycarbonyl)glycinehydrazide 
• 439916-93-5 C₂₈H₄₁N₃O₁₁ 
• 439916-95-7 C₂₉H₄₃N₃O₁₁ 
• 439916-97-9 C₃₇H₅₁N₃O₁₁ 

Relevant articles and documents

Original and efficient method for the preparation of N-aminoamide pseudodipeptides in high optical purity

N-Aminoamide pseudodipeptides ZAAΨ[CO-N(NPht)]-AAOR can be easily obtained via the Mitsunobu protocol by using α-hydroxyesters as alcohol partners and aminoacid phthaloyl hydrazide derivatives as acidic partners. The direct conversion of the phthaloyl group into tert-butyloxycarbonyl can be performed in a three-stage one-pot protocol.