440327-39-9Relevant articles and documents
Novel enzymatic synthesis of levulinyl protected nucleosides useful for solution phase synthesis of oligonucleotides
Garcia, Javier,Fernandez, Susana,Ferrero, Miguel,Sanghvi, Yogesh S.,Gotor, Vicente
, p. 3533 - 3540 (2007/10/03)
An efficient synthesis of 3′- and 5′-O-levulinyl-2′- deoxy- and 2′-O-alkylribonucleosides has been developed from appropriate nucleosides by enzyme-catalyzed regioselective acylation in organic solvents. Several lipases were screened in combination with a
