440363-05-3 Usage
General Description
3-Iodo-5-trifluoromethyl-1H-indole is a chemical compound with the molecular formula C9H5F3IN. It is a halogenated organic compound that consists of a five-membered ring fused to an indole ring structure. 3-Iodo-5-trifluoromethyl-1H-indole is a derivative of indole and contains a trifluoromethyl group and an iodo substituent. It is used in the field of organic synthesis and medicinal chemistry for the development of pharmaceutical drugs and as a building block for the synthesis of various complex molecules. 3-Iodo-5-trifluoromethyl-1H-indole has been studied for its potential pharmacological activities and is used as a reagent in chemical reactions for the preparation of various biologically active compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 440363-05-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,0,3,6 and 3 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 440363-05:
(8*4)+(7*4)+(6*0)+(5*3)+(4*6)+(3*3)+(2*0)+(1*5)=113
113 % 10 = 3
So 440363-05-3 is a valid CAS Registry Number.
InChI:InChI=1S/C9H5F3IN/c10-9(11,12)5-1-2-8-6(3-5)7(13)4-14-8/h1-4,14H
440363-05-3Relevant articles and documents
Practical syntheses of 5-trifluoromethyl-1H-indoles
Parmentier, Jean-Gilles,Poissonnet, Guillaume,Goldstein, Solo
, p. 465 - 476 (2002)
Short and convenient syntheses of 5-trifluoromethyltryptamine and 5-trifluoromethyltryptophole have been realized via a regioselective, palladium catalyzed, coupling/annulation method involving functionalized alkynes and 2-iodo-4-trifluoromethylaniline. A new and improved approach for the preparation of 5-trifluoromethyl-1H-indole is also described.
